GI Tract
  • A Minimally Invasive Endoscopic Procedure Instead of Bariatric Surgery?

A Minimally Invasive Endoscopic Procedure Instead of Bariatric Surgery?

Endoscopic sleeve gastroplasty (ESG) delays gastric emptying, induces early satiation, and significantly reduces body weight, researchers report in the January issue of Clinical Gastroenterology and Hepatology. ESG could therefore be an alternative to bariatric surgery for some patients with obesity. Although bariatric surgery is the most effective therapy for obesity,

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  • Hepatosplenic Lesions from Cat Scratch Disease

Hepatosplenic Lesions from Cat Scratch Disease

Researchers describe an unusual case of cat scratch disease, with hepatosplenic involvement, in the January 2017 issue of Clinical Gastroenterology and Hepatology. Sean K. Verma et al report on a 28-year-old man with no past medical history presented with fevers, chills, abdominal pain, night sweats, 3 weeks of weight loss,

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  • How Does Transforming Growth Factor beta Suppress Colorectal Tumor Development?

How Does Transforming Growth Factor beta Suppress Colorectal Tumor Development?

Researchers review the mechanisms by which loss of transforming growth factor beta (TGFB) proteins contribute to development and progression of colorectal cancer in the January 2017 issue of Gastroenterology. Development and progression of colorectal cancer involve loss of tumor suppressor proteins, including transforming growth factor beta (TGFB) family members. In colon

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  • Can a Smartphone App Monitor IBD Activity?

Can a Smartphone App Monitor IBD Activity?

Researchers have developed a mobile health index for remote monitoring of patients with inflammatory bowel diseases (IBD) that could be incorporated into a smartphone app. These findings are reported in the December issue of Clinical Gastroenterology and Hepatology. The shift from symptom-oriented to prevention-oriented care delivery has accelerated the development of

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  • Do Relatives of Patients With IBD Also Have Intestinal Dysbiosis?

Do Relatives of Patients With IBD Also Have Intestinal Dysbiosis?

The intestinal microbiota of many healthy, first-degree relatives of patients with inflammatory bowel diseases (IBD) is dysbiotic, signifying a pre-disease state, low-level inflammation, and susceptibility to IBD, researchers report in the November issue of Cellular and Molecular Gastroenterology and Hepatology. Changes in the intestinal microbiome are involved in the pathogenesis

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  • Can Yoga Reduce Symptoms of IBS?

Can Yoga Reduce Symptoms of IBS?

Yoga might be a feasible and safe adjunct treatment for irritable bowel syndrome (IBS), a systematic review shows in the December issue of Clinical Gastroenterology and Hepatology. The review found evidence for beneficial effects of yoga on gastrointestinal (GI) symptoms, quality of life, and anxiety, although further studies are needed. IBS is

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  • How Does Inflammation Lead to Anemia?

How Does Inflammation Lead to Anemia?

Researchers report a mechanism by which inflammation contributes to development of anemia in the November issue of Gastroenterology. The process involves increased liver expression of a microRNA that reduces production of erythropoietin in kidney. Strategies to block this miRNA might help prevent anemia in patients with chronic inflammation. Anemia is associated

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  • Can Histologic Features Identify Patients with GERD?

Can Histologic Features Identify Patients with GERD?

Total epithelial thickness is a robust histologic marker that can be used in detection of gastroesophageal reflux disease (GERD), researchers report in the November issue of Clinical Gastroenterology and Hepatology. GERD can be a challenge to diagnose because its symptoms overlap with those of other disorders. Endoscopy and esophageal pH

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  • How Could the Intestinal Microbiota Contribute to Celiac Disease?

How Could the Intestinal Microbiota Contribute to Celiac Disease?

Bacteria in the small intestine metabolize gluten differently, to increase or decrease its immunogenicity, researchers report in the October issue of Gastroenterology. This interaction between microbes and gluten could help determine the risk for autoimmune enteropathy in genetically susceptible individuals and underlie the reported association between dysbiosis and celiac disease.

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  • Candy Cane Esophagus From Hot Tea

Candy Cane Esophagus From Hot Tea

Researchers describe a patient with a “candy cane appearance” of the esophagus, due to acute thermal injury, in the October issue of Clinical Gastroenterology and Hepatology. Upon further investigation, the authors found that the patient had poured hot boiling tea into his throat. Arun AC and Jenish Rajma describe the case of a 19-year-old

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