Press Highlights
  • Molecular Subtypes of Pancreatic Cancer Identified

Molecular Subtypes of Pancreatic Cancer Identified

Pancreatic tumors can be divided into 4 classes based on molecular and genetic features, researchers show. The findings reveal differences in the development of different subtypes of pancreatic cancer that could lead to new therapeutic targets and individualized therapy. Peter Bailey et al performed an integrated genomic analysis of 456 pancreatic

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  • Intestinal Microbiota Protect Children From Malnutrition

Intestinal Microbiota Protect Children From Malnutrition

Three new studies show that intestinal bacteria protect children from malnutrition and allow them to benefit from breast milk. Malnutrition, the world’s leading cause of death before age 5, is a persistent challenge that is not always remedied by improvements in nutrition. This is because the community of gut microbes regulate growth,

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  • Restoring Vaginal Microbiota to C-Section Babies

Restoring Vaginal Microbiota to C-Section Babies

Babies born by Cesarean section (C-section) are not always exposed to bacteria and other microbes present in the birth canals of their mothers—a factor that some studies have associated with health risks later in life. Now, researchers present preliminary data indicating that microbial communities could be at least partly restored

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  • Biomarker of Early-stage Aggressive Colon Cancer

Biomarker of Early-stage Aggressive Colon Cancer

Lack of the biomarker CDX2 identifies a subgroup of patients with high-risk stage II colon cancer who appeared to benefit from adjuvant chemotherapy. These patients are usually treated with surgery alone. The findings come from a study published online January 21 in the New England Journal of Medicine. Piero Dalerba

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  • 5 Hospitalized and 1 Dead in Clinical Trial in France

5 Hospitalized and 1 Dead in Clinical Trial in France

Five men were hospitalized and 1 died after a drug trial in France, the country’s health minister announced on January 15. Marisol Touraine, the minister for social affairs, health, and women’s rights, said in a statement that her office was informed the evening of January 14 about a “serious accident”

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  • The Iceman’s Gut Microbes Cometh

The Iceman’s Gut Microbes Cometh

Analysis of microbes from the gut of the Iceman—a 5300-year-old Copper Age European glacial mummy—provides insights into not only his health status right before he was murdered, but migration patterns of humans and their microbiota. Helicobacter pylori, one of the most prevalent human pathogens, is globally dispersed but has a

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  • Almost 31,000 US Deaths Associated with Alcohol Use in 2014

Almost 31,000 US Deaths Associated with Alcohol Use in 2014

Americans are drinking themselves to death at a record-breaking rate, according a December 18 report from the Center for Disease Control and Prevention (CDC). In the Morbidity and Mortality Weekly Report, Rose A. Rudd et al reported that “30,700 Americans died from alcohol-induced causes, including alcohol poisoning and cirrhosis.” This

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  • Gilead Sells Sofosbuvir to Egypt for About $10 per Pill

Gilead Sells Sofosbuvir to Egypt for About $10 per Pill

In Egypt, pharmaceutical companies are testing a complicated deal to sell hepatitis C drugs at a fraction of their usual cost while imposing tight restrictions intended to protect lucrative markets in the West. According to the New York Times, Gilead Sciences Inc. is selling its sofosbuvir to the Egyptian government

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New Treatment Approved by FDA for Lysosomal Acid Lipase Deficiency

The Food and Drug Administration (FDA) approved a drug called sebelipase alfa (Kanuma) as the first-ever treatment for lysosomal acid lipase deficiency (LAL)—a rare inherited disorder. LAL deficiency causes a build-up of fats within the cells of various tissues that can lead to liver and cardiovascular diseases and other complications.

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  • Medicaid Denies Almost 50% of Prescriptions for Hepatitis C Drugs in 4 States

Medicaid Denies Almost 50% of Prescriptions for Hepatitis C Drugs in 4 States

Medicaid programs in Delaware, Maryland, New Jersey, and Pennsylvania denied nearly half of all claims in the past year for direct-acting antiviral (DAA) hepatitis C drugs, according to an analysis of pharmacy data presented at the American Association for the Study of Liver Diseases 2015 Liver Meeting. The finding confirms

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