Press Highlights
  • Antiviral Agents Show Safety and Efficacy in Hard to Treat Patients with HCV Infection

Antiviral Agents Show Safety and Efficacy in Hard to Treat Patients with HCV Infection

Direct-acting antiviral agents against the hepatitis C virus (HCV) are proving to be effective in even the most difficult to treat patients—including those with chronic kidney disease, decompensated cirrhosis, and disease recurrence after transplantation. Results from clinical trials of these challenging patients were reported at the 2015 EASL International Liver

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  • Genetic Analysis of Tumors Could Improve With Proper Controls

Genetic Analysis of Tumors Could Improve With Proper Controls

Up to two thirds of mutations identified in tumors also exist in matched, non-tumor tissues, researchers have found. It is therefore important for oncologists to identify the mutations that actually promote the progression of a patient’s tumor before selecting therapy. The finding, published in Science Translational Medicine on 15 April, comes

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Cheap Allergy Drug Prevents HCV Infection of Hepatocytes

An over-the-counter allergy drug may be repurposed to treat patients with hepatitis C, researchers show. Chlorcyclizine, which costs about $0.50 a tablet, could offer a low-cost alternative or addition to treatment for patients with hepatitis C virus (HCV) infection. Direct-acting antiviral therapies can cure hepatitis C, but their high cost—which

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Genetic Analysis of Icelandic Population Provides Disease Insights

Scientists in Iceland have performed an unprecedentated genetic analysis of an entire nation, associating previously undiscovered mutations with disorders such as liver disease and gallstones. In 4 articles published last week in Nature Genetics, researchers at DeCODE, an Icelandic genetics firm owned by Amgen, described sequencing the genomes of 2636

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  • Hepatitis C Drugs Might be Cost Effective but Demand Could Bust the Healthcare Bank

Hepatitis C Drugs Might be Cost Effective but Demand Could Bust the Healthcare Bank

Treating patients with hepatitis C virus (HCV) infection using recently approved direct-acting agents can be cost effective, but will also have substantial effects on healthcare costs, researchers show. Recently approved drugs cure more than 90% of patients with hepatitis C and could make the liver disease rare in the United

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  • Veggie Diets, Especially With Fish, Cut Colorectal Cancer Risk

Veggie Diets, Especially With Fish, Cut Colorectal Cancer Risk

A vegetarian diet, especially one that includes fish, significantly reduces the risk of colorectal cancer, a large new study reports. These findings could lead to new strategies for cancer prevention. In the Adventist Health Study 2, researchers had 77,659 men and women from Seventh-day Adventist churches nationwide complete well-validated questionnaires

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  • An Effective and Long-lasting Hepatitis E Vaccine

An Effective and Long-lasting Hepatitis E Vaccine

A long-term study of a hepatitis E virus (HEV) vaccine showed that it is 86.8% effective and that immunity can last for up to 4.5 years. In a blinded, placebo-controlled, phase 3 trial, Jun Zhang et al randomly assigned 112,604 healthy adults in Dongtai (in the Jiangsu province of China)

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  • Food Emulsifiers Increase Intestinal Permeability to Promote Inflammation

Food Emulsifiers Increase Intestinal Permeability to Promote Inflammation

Food additives commonly used to thicken and stabilize processed foods disrupt the intestinal microbiota to cause inflammation, researchers found in a study of mice. Emulsifiers are added to foods to hold together mixtures of fat and water, which would otherwise separate. Healthy mice fed a diet containing commonly used emulsifiers (1%

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  • Medicare to Release Physician-Payment Records Each Year

Medicare to Release Physician-Payment Records Each Year

The Federal government will begin releasing Medicare physician payment records annually, allowing public access to information about how billions of dollars are spent each year on payments to providers. The Centers for Medicare and Medicaid Services announced that the government has decided to update the information annually, despite the concerns of groups such as

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  • President Seeks Extra Funding to Fight Antibiotic-resistant Bacteria

President Seeks Extra Funding to Fight Antibiotic-resistant Bacteria

The Obama administration hopes to double federal funding for research of antibiotic-resistant bacteria. The President’s fiscal year (FY) 2016 Budget nearly doubles the amount of Federal funding for combating and preventing antibiotic resistance, to more than $1.2 billion, including more than $650 million for the National Institutes of Health (NIH).

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