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  • Celiac Disease Risk Not Affected by Early Diet

Celiac Disease Risk Not Affected by Early Diet

Two studies have shown that neither breastfeeding nor timing the start of gluten-containing foods makes a difference in development of celiac disease in children at risk. The AP reported that the studies, published October 2 in the New England Journal of Medicine, show that there is no early window of

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Metabolic Markers of Early-Stage Pancreatic Cancer

Researchers have identified a marker of early-stage pancreatic cancer that might be used to detect the disease in its initial, more treatable stages. Pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, has been linked with obesity and glucose intolerance, but few studies have evaluated levels of circulating

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Adverse Effects of Artificial Sweeteners

Consumption of non-caloric artificial sweeteners can alter the gut microbiota to increase risk for glucose intolerance, according to a study in mice and humans. A study published online Sept. 17 in Nature showed that non-caloric artificial sweeteners (NAS), among the most widely used food additives worldwide, promote development of glucose

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A Genetic Variant Increases Susceptibility to Pancreatitis from Thiopurines

Geneticists have identified a variant that increases risk for pancreatitis 4-fold in patients receiving thiopurine drugs. Pancreatitis occurs in approximately 4% of patients treated with the thiopurines azathioprine or mercaptopurine. Its development is unpredictable and almost always leads to drug withdrawal. In a study published September 14 in Nature Genetics,

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FDA Approves New Obesity Drug

The US Food and Drug Administration (FDA) approved the third new prescription drug for obesity since 2012. The drug, Contrave, to be used along with a low-calorie diet and exercise regimen, was approved for treatment of obese adults (body mass index [BMI] of 30 or greater) or overweight adults (BMI

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Social Media Helps Identify Sources of Food Poisoning

The Chicago Department of Public Health (CDPH) has developed an innovative strategy to rapidly identify foodborne illness outbreaks and locate their sources. The approach involves collaboration between public health professionals and the public, via social media. The CDPH launched FoodBorne Chicago, which tracks Twitter messages using a supervised learning algorithm.

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NIH Grants Awards to “Follow That Cell”

The National Institutes of Health is challenging science innovators to compete for up to $500,000 in prizes for developing new ways to track the activities of single cells in complex tissues. The NIH’s “Single Cell Analysis Challenge”, funded by the NIH’s Single Cell Analysis Program (SCAP), will provide awards to investigate methods

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Different Meta-analysis Strategies Produce Different Findings

Estimates of treatment outcomes based on meta-analyses differ depending on the strategy of analysis used, statisticians report. Meta-analyses of randomized clinical trials are generally considered to provide among the best evidence of efficacy of treatments. However, it is not always clear which trials should be included in a meta-analyses. Meta-analyses

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IOM Calls for Changes to Graduate Medical Education Funding

Tighter oversight is needed for more than $15 billion spent yearly on doctor training in the US, according to a new report that’s already being attacked by medical centers that provide the education. The report, released July 29 by the Institute of Medicine (IOM), calls for per-resident funding based on outcomes

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Researchers Characterize 4 Molecular Subtypes of Gastric Cancer

Stomach cancers fall into 4 distinct molecular subtypes, researchers report. This information could lead to new strategies to treat patients with specific types of gastric cancer. In the study, published online July 23, 2014, in Nature, researchers with The Cancer Genome Atlas Network (TCGA) report findings that could change how

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