Causes of Chronic Nausea and Vomiting

Chronic nausea and vomiting in patients with normal gastric emptying is a significant medical problem that is indistinguishable from gastroparesis and might be a separate clinical entity, according to Pankaj Pasricha in the July issue of Clinical Gastroenterology and Hepatology.

Chronic nausea and vomiting in patients that do not have any obvious structural abnormalities is a difficult problem for physicians and patients alike. When the nausea and vomiting are associated with a delay in gastric emptying, the syndrome is called gastroparesis. However, some patients have no demonstrable abnormalities in gastric emptying, and are a challenge to diagnose and manage.

To study this disorder, Pasricha et al. collected and analyzed data from 425 patients with chronic nausea and vomiting; 319 (75%) had delayed emptying, defined by the results of a standardized, low-fat meal, and 106 had normal gastric emptying.

Pasricha et al. found that patients with symptoms of chronic nausea and vomiting, but normal gastric emptying, were indistinguishable from patients with classical gastroparesis by most demographic and clinical criteria. Symptom severity indexes were similar between groups for nausea, retching, vomiting, stomach fullness, inability to complete a meal, feeling excessively full after meals, loss of appetite, bloating, and a visibly larger stomach. There were no differences in health care utilization, quality of life indexes, depression, or trait anxiety scores.

Importantly, patients with the syndrome were not adequately captured by the stand-alone criteria for the Rome III diagnoses of chronic idiopathic nausea and functional vomiting. In an accompanying editorial, Nathaniel Winstead states that the Rome Committee should improve the criteria for functional vomiting and chronic idiopathic nausea.

The  pathogenesis of nausea and vomiting in these patients is unexplained—it is not clear whether this is a distinct syndrome, a heterogenous collection of unidentified etiologies, or a type of gastroparesis that changes over time.

Pasricha et al. propose that these patients might have abnormalities in gastric function that are more subtle than those found in classical gastroparesis. Techniques used to measure solid gastric emptying might not capture the entire spectrum of gastric dysfunctions—the authors point out that nearly a third of patients believed to have normal solid gastric emptying have delayed liquid gastric emptying.  Aberrant afferent signaling via the vagal of splanchnic nerves, or changes in hormone levels, might also account for the symptoms.

Pasricha et al. did associate a history of binge drinking with chronic unexplained nausea and vomiting with normal gastric emptying. Winstead suggested that ethanol might be toxic to the enteric nervous system in some individuals.

Winstead states that one of the most interesting features of the study was the stability of the disorder—after nearly 1 year, very few patients had a change in diagnosis. He states that we must determine whether this is a primary disorder, a highly selected group of very ill patients with severe functional dyspepsia, or a collection of different problems leading to a final common pathway of chronic unexplainable nausea.

More information:

Read the article online.
Pasricha PJ, Colvin R, Yates K, et al. Characteristics of patients with chronic unexplained nausea and vomiting and normal gastric emptying. Clin Gastroenterol and Hepatol 2011;9:567–576.

Read the accompanying editorial.
Winstead N. The challenges of chronic nausea and vomiting and normal gastric emptying. Clin Gastroenterol and Hepatol 2011;9:534–535.

57 Comments

  1. Avatar
    Tina Schabell March 06, 2012

    My mother has lived at least 2-3 years now with chronic nausea which now she has been having vomited with it for over 6 months. She has had multiple stomach empting studies with mixed results. 2 out of 3 studies stated that they were normal. EGD was done with biopsy done with no new results except lots of imflamation in esophogus and stomach. no cancer or bacteria was found.. She is nauseated and vomits if she does eat or drink anything and if she don’t. She is an overweight woman which has lost over 30 pounds in just a couple of months which all the doctors can say good your lossing weight. Yes I agree it’s good for weight lost but not like this and having no quality of life. Some days she can’t even hold her head up. She is diabetic type 2. one doctor told her she should only drink water. How unreal is that? We are desprate to find out what is going on and stop this. She has also tried meds to stop nausea and vomiting without success. Please if anybody has any sugestions or referrals please contact me by email..I don’t know how much longer she can handle this. Thanks, Tina

    • Avatar
      Kat Hamilton March 27, 2012

      I was reading your letter and am surprised how similar your mother is to mine. I have been searching the Internet trying to find answers but have not found anything. She has had the same nausea for two years and over the past 6 months has had severe vomiting. I am very concerned and even after she was hospitalised for five days have no answers. I was curios if they have diagnosed your mother or if you might have any suggestions.
      hope your mother is doing better
      Kat

  2. Avatar
    annette March 17, 2012

    Tina, There is a very real possibility with the diabetes and length of time dealing with this that your mom may have to go in the hospital for a few days so they can throw everything at what is going on with her…the length of time suggests that she may now be protien, vitamin, or electrolyte deficient or out of balance all of which will add to and continue the nausea. All three of these plus imbalances in her diabetic glucose levels can all cause severe nausea. Please also have them check gall bladder and pancrease.

    • Avatar
      Anonymous August 02, 2012

      They have told my mom she is malnuristed but they dont do anything about it. She had gallbladder removed and hysterectomy years ago before all this started. No relief in site. A new GI doctor thinks its too many cokes but she cant even hold it down long enough to b the problem.

      • Avatar
        Teresa September 22, 2019

        I do not know if anyone else has noticed that every comment has been happening females, that is strange! I have a friend that her elder mom started this a few years ago, it it is ‘not constant, here goes in spells? Like it has been about a year since her last bout. She is in the hospital now going through have test tomorrow. As far as the young girl that bleeds all the time that is not normal, go to a GYNECOLOGIST and demand test such as a laparoscopy,! My pap – smear came back negative, but stressed all the bleeding and clots…. the laparoscopy found a mass…. do not mess around with this, and if he doesn’t do it find a good reputable Gynecologist that will! What people do not realize with their negative comments, such as being in your head etc…. no one wants to feel like this…. they have no clue!

  3. Avatar
    Nancy Stapleton April 05, 2012

    My daughter Kyla is now 16 years old. She has been vomiting multiple times a day for 2 years. She has very little nausea. She is now having pain and the episodes have become more violent. The doctors say she has EE syndrome and slight SMA syndrome but the x-ray shows the food has room to pass and so it is a mystery why my daughter is living this nightmare. I am frustrated with doctors… More meds that don’t work. I hope Kyla gets a chance to live with out this. She is not able to do so many things now… It effects her whole life. Help!

    • Avatar
      penny May 08, 2013

      i know what you mean i cant do many things or enjoy many things cause of me being so nausea all the time and mostly in the morning im really bad i feel like im gonna die its so bad. and im nausea all day but it worsen by morning. i even take zofran and phenegrin and sometimes they help but most of the time it doesnt. i wish my dr would find out what the heck is wrong with me.

    • Avatar
      Daniella September 02, 2019

      Hello, Please update me if you find anything helpful. I have the same symptoms as your daughter except I also feel very nauseous in addition to vomiting. It has been 13 years and I had learnt to manage it a lot more now but it’s still very very hard. So many times, I just throw up in public and it’s very embarrassing , like on the public transportation, while working, while eating out with friends, etc… HELP!

  4. Avatar
    Vickie Nevels April 22, 2012

    Thank the Lord, I’m not alone. Finding this article and knowing it’s happening to others without a true diagnosis is great but disheartening. I’m a 49yo female with chronic nausea, retching and vomiting. It has gotten so bad I’m basically a shutin. I constantly must wear pads because the gagging is so forceful I usually wet my pants. It doesn’t matter of I eat or not the NV is always present. I also have lost weight (49#). This is no way to live. I can’t plan anything. I have had several gastric empting test as well with mixed results. I eat Zofran like candy trying to stop the nausea. My health issues are GERD, RA, Fibromyalgia, and Barretts Esophagus. I to have searched the internet for answers. So far this is the only site that I have found others like me. Thank all of you for your postings they really helped me. Prayers to all of you suffering like me, hopefully an answer will soon be available.

    • Avatar
      Z. Monique August 20, 2012

      I am so sorry that other people out there are suffering with this issue. However it is a bit comforting knowing that I am not alone. I am a 31 yr old woman and I have been dealing with this since I was a teenager. I vomit just about everyday and sometimes its so bad I know better than to leave the house because it happens so many times in one day. Although I haven’t been diagnosed with anything else, I do not believe I have diabetes or any other ailments. I do have menstraul issues though. I am constantly bleeding and it VERY rarely stops but I never get cramps so its mostly just an inconvience of always having to wear pads or tampons. Most people don’t understand and say that the nausea and vomitting are all in my head but I know its not. I went to the doctor once and he told my Mom it was all in my head and that I need to stay relaxed. The problem with that is I can be happy and relaxed and the next minute I am vomitting. I have tried to document when it happens and I have come up with the fact that I vomit when I get hot, I vomit after riding the bus or sitting in a car, I vomit after meals, I vomit when I am hungry, I vomit when i wake up, I vomit when I am sad or excited…I could go on but the point is that anything can trigger my nausea and vomitting. People have given me over the counter drugs which just make me sick and I have also tried teas. If anyone knows more about this please let me know how I can get some relief. Its so hard to deal with and frankly its embarassing vomitting in public because I don’t have any control over it. Thanks to everyone who is sharing on this forum! It truly helps when people understand what you are going through rather than thinking you are crazy.

      • Avatar
        Angel March 20, 2013

        Have you researched for C.V.S.? Cyclic Vomiting Syndrome? I am thinking this is going to be my diagnosis. ;-(

    • Avatar
      Angel March 20, 2013

      Here is the same for me. I am 43 yro mother of 3, married 24 yr, ill with these episodes that have no “lab-identifiable” cause now for nearly 4 yrs. I’ve missed so much with my kids. I am in search of ANYONE who can relate to this tortutous condition!

      • Avatar
        Vickie March 21, 2013

        I also suffer from chronic nausea and vomiting for the last 17 months. I can’t plan anything so I’m like a prisoner in my home. I also must wear a pad because of the forcefulness of my retching. I’m a 50 yo female who unfortunately can’t offer any help because no doctor can tell me what’s wrong. I’ve seen a gastroenterologist, neurologist, endocrinologist, internists and a psychiatrist and ALL of them look at me like I’m looney. They don’t see how someone could vomit 6-12 times a day. Even loosing 49 pounds in 5 months doesn’t convince them. My prayers go out to everyone suffering with this and no answers. It’s a tough road to travel

        • Avatar
          Deepak Sharma August 06, 2019

          When appearing shortly after a meal, nausea or vomiting may be caused by food poisoning, gastritis (inflammation of the stomach lining), an ulcer, or bulimia. Nausea or vomiting one to eight hours after a meal may also indicate food poisoning. Nausea is an uncomfortable but non-painful feeling in the back of your throat, chest, or upper stomach. Nausea causes a queasy, unsettled feeling that can make you want to throw up (vomit). … Some people experience nausea even when they are sleeping. Chronic nausea can include symptoms that are difficult to describe….(mygenericpharmacy)

    • Avatar
      penny May 08, 2013

      I also eat zofran like candy I also take phenegrin like candy cause zofran alone doesnt help and with the both taken together helps some but i still am nausea and i dont vomit all the time just really really nausea all the time and it scares me and sometime when i get that way i got to use the bathroom number 2 and i get hot and cold and i feel like im gonna pass out with it to.

  5. Avatar
    Deborah April 29, 2012

    i am 53 and have had chronic vomiting for about a year now. I also have type II diabetes. I have had several tests done to try to figure out the cause but so far I have gotten no real answers. I also have depression and the vomiting doesn’t help me to feel good about myself. Sometimes I feel the doctors don’t believe that I vomit everyday. I have had professionals tell me it’s in my head and others have said for me to deal with it. I would like to see them deal with it for just a week and see if they like it because I sure don’t. I am glad to know that I am not the only person with this problem because I was feeling so alone. I am sorry that others are going through this. Hopefully soon there will be an answer for us.

    • Avatar
      Vickie Nevels April 30, 2012

      Hi, Deborah welcome to the site. This is the only site I’ve found where individuals can support each other. I also wish the doctors had this mess for just one week. If they did there would be a cure ASAP. I noticed that other people like yourself have diabetes. I’ve read that n&v goes with that alot. Why I’m not sure. I do not have diabetes but I do have other medical issues like RA, Fibromyalgia, and GERD/Hital Hernia. I’m scheduled for an upper GI study on Tuesday and then alot of gastric XRays starting Thursday. I hope something is found. My now ex husband had very little patients and with my illnesses. I have been dealing
      with depression for quite sometime and also deal with anxiey

      • Avatar
        Deborah April 30, 2012

        Hi, it was nice to hear from you. I am sorry that others have this problem but at the same time I am glad I am not alone. I have had professionals tell me it is in my head,i have to deal with it and to pray to God. I recently changed GI doctors to see if he has anything new to offer because I was getting nowhere with the last one. I did have a test a few weeks ago and the results were normal. I see him again in a couple of weeks and I hope he has something else to offer. I hope you find some answers from the tests you have this week. My boyfriend is trying to be supportive but I know it is hard on him because he loves me but at the same time it’s not happening to him so he sometimes is not there for me, but at least he tries. God luck.

  6. Avatar
    Kathy May 16, 2012

    I was disgnosed with Crohns 4 yrs ago and had it a year before. I have serious nausea vomiting ever since, with small intervals of peace. Right now been in hospital 4 times in 4 weeks. Need the IVs to get rehydrated, pain meds, stronger antinausea. It also triggers migraines. My gastro guy is stymied. ER is too, as is Internal Med guy. 5 yrs of NV has made me a crazy woman. I am SO glad to at least hear I am not alone. I want my life back. So does my family….

  7. Avatar
    Anonymous June 24, 2012

    Has anyone had a hysterectomy and has the chronic vomiting and nausea?

    • Avatar
      Vickie Nevels June 27, 2012

      I am still suffering with chronic N/V. Gastric emptying and Scopes are normal. I tried the drug Colostipol, which is supposed to bind with bile to decrease nausea, but all it did was cause severe stomach, face, feet and ankle swelling. It also caused terrible constipation. Now they are leaning toward it being neurologicAl and I’m having a MRI to rule out a brain tumor or lesion on the brainstem. Definitely don’t want that but at least it would be an answer.

      • Avatar
        Vickie Nevels July 02, 2012

        Still no answer on the brain tumor, but my dr. gave me a new drug called Domperidone. It has been truly sent from God. After vomiting 12 – 16 times a day for a solid year and nausea so bad you can’t raise your head I finally have some relief. I have not vomited one time in 5 days and very little nausea. Ask your Dr. for some of this drug. I hope it works for all of you.

    • Avatar
      Rene February 02, 2013

      Hi! I am a 42 yo woman. I have been dealing with chronic nausea and vomiting, Ive tried every form of nausea med that the doctors have thrown at me, back in 2010, I went into one of our leading hopitals with pain on my right side, I had some scar tissue built up because of Endometriosis. while in the or, the dr thought my appendix looked slighly enlarged, so he decided to remove it, witjout realizing he had perferated my colon.
      Which lead to a 9 month stay in the hospital with a colostomy bag placed, and an additiomal 12 abdominal surgeries. I still had the nausea and vomitimg which started after my 1st surgery. I had it ever since. I have tried every remedy that I have heard of or read about. back in May of 2011 Ihad the colostomy bad taken down, Thank God for that.
      I am still having the n/v episodes, which are worse and more frequent. Now I get to add the stress of adv stage 3 breast cancer.I keep hoping I will rin in to someone who has some miacle answer, but no such luck.
      I keep praying for a cure of some sort, and of course for the strenght to fight the cancer as well. My babies need me, and I so desperatly need them.
      My thought and prayers are with you all.

      • Avatar
        Vickie February 04, 2013

        My prayers go out to you and your family. I pray that you win your battle with cancer. My chronic and vomiting started at age 48 after a total knew replacement. It’s been a year and 5 months of constant n/v. Of course every doctor I have seen says their is no connection to the surgery. I, like you, have taken every medication and test they throw at me. While at my Neurologist for my migraines I told him about the chronic n/v. I explained all the meds and test I had received. He said well lets think out of the box. He told me that we have nausea and vomiting centers in our brain as well as in our stomach. He put me on a drug called klonopin. He started at 1mg. Surprisingly the nausea slowed down. We increased to 2mg and my nausea is almost memory. I still have n/v once a week or so, but that beats every and all day long. I also got some relief in vomiting after I got my chronic constipation better. I had been given every drug possible to help with chronic constipation. I eat plenty of fiber and drink plenty of water but still constipation persisted. I’m a chronic pain patient so the constipation is due to pain meds. Once again it was my Neurologist that told me to eat dried fruit. He said stuff like trail mix that combine dried fruit and nuts would do the trick. Once I tried the stuff and got better regulated I was able to stop the laxative meds. So, with the klonopin and
        the trail mix my chronic nausea and vomitiny are much more managed. If I miss a dose of klonopin the n/v starts within 12 – 24 hrs. Sorry this was so long and I hope it helps someone.

  8. Avatar
    Anonymous July 02, 2012

    Chronic Vomiting Synrdrome Association

    • Avatar
      Anonymous July 02, 2012

      CVSA.org
      Check it out!

  9. Avatar
    em July 09, 2012

    I’ve read parathyroid gland problem is also a cause and linked with diabetes, blood tests can check this

  10. Avatar
    em July 09, 2012

    oops! it’s gastroparesis that’s linked with diabetes, because of the effect of the diabetes on the vagus nerve affecting gut motility. parathyroid problems can cause excess acid secretion in the stomach. gastroparesis can be intermittant I think so may not always show up on tests.

  11. Avatar
    Ree August 13, 2012

    So glad to know, i’m not alone. My Mom had this happen 4 months ago, and now it’s happeing again! This is no way to live. You feel so helpless! And going back and forth to the hospital is way to costly.

  12. Avatar
    Anonymous September 10, 2012

    Roberta says:
    I had a Colectomy Nov 3, 2011 where over 30 inches of my intestines were removed. I was in the hospital for 17 days, and off work for almost 12 weeks. I felt pretty good when I returned to work, but however in May of 2012 I started having stomach problems again. I went to the doctor again, and found that I had an Abdomnal Hernia, and was told that it would have to be repaired. I rolled the thought around in my head for good 6 weeks until I decided to have it repaired. On July 24, 2012, I again went under the knife. In this procedure I also had the excess fat removed from my stomach. Here it is September 2012, and I am suffering from cronic nausia after this surgery. It will not go away. I cannot go anywhere or do anything. I have taken and used everything I can think of, but it will not go away. Does anyone out there know what I am talking about or have had the same problem after surgery. Oh yes, I am also doctoring an open would in the lower part of my abdomon which occurred and was readmitted to the hospital twice and the emergency room more than 6 times.

  13. Avatar
    Anonymous September 10, 2012

    I had a Colectomy Nov 3, 2011 where over 30 inches of my intestines were removed. I was in the hospital for 17 days, and off work for almost 12 weeks. I felt pretty good when I returned to work, but however in May of 2012 I started having stomach problems again. I went to the doctor again, and found that I had an Abdomnal Hernia, and was told that it would have to be repaired. I rolled the thought around in my head for good 6 weeks until I decided to have it repaired. On July 24, 2012, I again went under the knife. In this procedure I also had the excess fat removed from my stomach. Here it is September 2012, and I am suffering from cronic nausia after this surgery. It will not go away. I cannot go anywhere or do anything. I have taken and used everything I can think of, but it will not go away. Does anyone out there know what I am talking about or have had the same problem after surgery. Oh yes, I am also doctoring an open would in the lower part of my abdomon which occurred and was readmitted to the hospital twice and the emergency room more than 6 times.

  14. Avatar
    Kim September 22, 2012

    I have been having chronic nausea for the last 6 months. Retching in the morning. No vomiting. Have had many tests. All turn up negative. I was reading about the antidepressant Remeron being used to treat nausea. Was wondering if anyone has tried it and had success. I am now going to try a gluten-free diet and see if that helps.

  15. Avatar
    Vickie Nevels September 23, 2012

    I take Remeron nightly for sleep and it has no effect on my nausea. I , like you have morning wrenching and daily nausea. I have been having this problem for over a year with no relief. I have had every test possible with no answers. I haven’t tried a gluetin free diet. I’m interested in finding out how well it works for you.

  16. Avatar
    cynthia January 08, 2013

    My son has uncommon renal tubular acidosis. He has had chronic vomiting for the last 8 yrs. No one can figure out what is causing it. It complicates his RTA. He has had all kinds of gastric tests that all come back normal. He is going to die if this can’t be stopped. The vomiting causes his potassium to drop to dangerous levels. Which then causes his heart rate to become abnormal. He is hospitalized on average every two weeks.

  17. Avatar
    Monica50 March 19, 2013

    I am 50 years old and I I have had chronic nausea and vomiting for seven months now. (Spetember 2012) I have had every test under the sun done for it. They came to the conclusion I had severe Gastroparesis. My doctor sent me to one of the best doctors in Temple University Hospital. I got more tests done on it, and now they say I have nothing wrong with me. I am vomiting every day up to six times a day. I had Botox injections given to me for the vomiting. It is a treatment for Gastroparesis but so far no results. It is frustrating. I have lost 26 pounds since this all started. I still think it is Gastroparesis.

  18. Avatar
    penny May 08, 2013

    Im 41 yrs old and i have chronic nausea everyday and im so nausea in the mornings really bad to the point i feel like im gonna die. and i hate this feeling. i want to start feeling better so i can enjoy my kids and my grandkids more. this is no life to be like this. im also dizzy sometimes with this nausea. i also passed out from getting so dizzy and a hot feeling and i have a bowel movement. i wish the drs would find out what the heck is wrong. cause i want to live life and not always laying down.

  19. Avatar
    Sophie June 02, 2013

    Hi. I got sick in november in florida and have felt nauseous since. Its now june. Ive had stomach emptying, a scope down my throat, all the blood work, MRIs, trips to the ER, gallbladder test, and everything has come back normal. Im so sick of feeling sick all the time!!! I never want to do anything anymore. I want to feel normal again.

  20. Avatar
    Aidan July 12, 2013

    Does your blog have a contact page? I’m having trouble locating it but, I’d like to send
    you an e-mail. I’ve got some recommendations for your blog you might be interested in hearing. Either way, great site and I look forward to seeing it expand over time.

  21. Avatar
    MIchele August 24, 2013

    no nausea but chronic projectile vomiting for about 6 months now, it comes on suddenly and I have vomited on my dog and other people because it comes so fast I dont feel it, I have not eaten in weeks and when I was it would come up within 20 minutes of eating so I gave up… I drink water to have something to puke because after the first spout comes the dry heaves… dont know what to do, nausea meds do not work

  22. Avatar
    Teresa November 11, 2013

    I am a 50 year old woman who has suffered the nausea for over 20 years and the vomiting started a year ago. I had my gall bladder removed two years ago and have hard cramping stomach pains that I am prescribed Donatell (a controlled substance) for high blood pressure and Hep -C. I have been scoped from both ends and the doctors just tell me I have stomach spasms and need to take a pill when it starts. I don’t leave home without the pills and a barf bag in my purse. I exercise regularly and watch my fat intake. I don’t drink or smoke and my weight was in the correct range for my height. I lost 10 lbs without trying before the vomiting started. Changed doctors twice and still know relief. The doctors are useless and a waste of money. I found that a little fiber in the mornings can help every now and then because it binds the bile in your stomach, too much and it binds you up a lot.

  23. Avatar
    JadeEclypse February 23, 2014

    I’ve been dealing with this for almost 1 year now. 29 year old female who began with general nausea/vomiting that progressively got worse. Got my gallbladder out because the symptoms were identical to my mother’s from two years ago and it showed constriction and stones, thought that would solve my problem. Unfortunately the nausea and vomiting only got worse.

    Every test has shown something different but ultimately they’re unremarkable. My upper GI showed a full stomach 13 hours later, my upper endoscopy was normal but my doctor was questioning auto-immune related inflammation, my gastric emptying study was completely normal. I had my most recent follow up with a PA that works for my doctor’s office who basically gave me that good old brush off feeling again because my tests are “unremarkable”. So is apparently my 30 pound weight loss without trying. They just drew blood to test for celiac disease, and I’ve a take home kit of breath tubes to test for overgrowth of intestinal fleura. I’m a registered nurse, have been for 7 years, I know what’s normal and what isn’t, and I know when a doctor is getting tired of dealing with something. I spent the last meeting with the PA feeling really disheartened, because at least the doctor seemed to want to make an effort to figure things out, where as she is quick to try and point fingers at random things -I- might be doing wrong to cause it. For instance, I take NSAIDS sometimes, because I have fibromyalgia and polyarthritis that we’re still in the process of working up, so since NSAIDS can cause nausea and vomiting, clearly my use of them for my joint and muscle pain is to blame. It was one big circular meeting where everything I said was rebutted to something else.

    All I know is, I’m 29, and this is not what I anticipated 29 feeling like. I do NOT have diabetes, yes I’m slightly overweight, but I do not have Hypertension, high cholesterol, or anything that should indicate why I spend almost every day nauseated, why foods I was eating a year ago SOUND completely disgusting and make me gag, or why I dry heave half the time and throw up sometimes.

    It gets so frustrating, being made to feel like it’s all in your head. I’ve no doubt stress complicates things, but that doesn’t mean it’s in my head and not a real problem. This article and these responses make me happy in a way, because it tells me that it isn’t just ME. It’s just nice to hear that I’m not completely alone in this.

    • Avatar
      Monkeypaw June 11, 2019

      Did they ever figure what happened? I am a 29 year old male who has had nausea and stomach pain for 9.5 months now. The doctors cannot figure out what is wrong. I had a gastric ulcer. It healed. But the stomach pain and nausea were still there even on the day it was verified healed. Six months later, still no more answers.

      Please let me know if you get a chance.

  24. Avatar
    xkyvqfyxj@gmail.com April 13, 2014

    I intended to draft you this tiny remark to be able to thank you so much yet again for these stunning pointers you have shared in this case.

  25. Avatar
    Starr January 12, 2019

    My best friend has had chronic, idiopathic nausea for over four years and it’s completely destroyed her quality of life. There is no rhyme or reason to her nausea. It’s not related to her diet, her mood, the status of her immune system, any related comorbities and/or infections, the weather, etc. It’s so frustrating. I wish there were a greater awareness about the suffering that never-ending nausea creates and a focus on treatments to help alleviate nausea even when there isn’t an underlying, identifiable “cause.”

  26. Avatar
    Jackie M. March 26, 2019

    Found this when trying to look for causes of my nausea. I’ve only had chronic nausea for a couple months, but it’s been so bad I’ve had to take a ton of time off work and even took a leave of absence. I have had gastric emptying, upper endoscopy, blood tests, and a CT scan. I’m not sure what the next step is, but it’s very validating to know I’m not alone in this. The doctors think it might be stress (I have an anxiety disorder), but I’ve had anxiety for fifteen years and never had this happen. I did have low B12 and folic acid levels, but those have been raised back up and no difference. I just want to get my life back under control.

  27. Avatar
    Thessaly March 31, 2019

    I started having chronic nausea out of the blue in January 2014. For nearly six months i retched up everything i ate, every single day, and would continue dry heaving, even after my stomach was completely empty. I have had ultrascans, CT scans, endless bloodwork, upper endoscopy. Everything is always “normal”.
    About a year in, i started having occasional “good days” which still meant being constantly nauseated, but without active retching.
    We are now 5 years in. I have had occasional bursts of “well ess” sometimes lasting a couple of months at a time, but just when i think its kinda over, i will have another “spell”. My “spells can last from 2 weeks to 2 months, where i feel almost constant nausea. Sometimes phenergan and zofran help, but they quite often do nothing at all.

    This has changed me from being very outgoing and adventurous bto being a virtual shut in. I often contemplate ending things, because i just cant picture living like this long term. It sucks the joy out of everything when you cannot socialize over a meal with other people.
    Sometimes i will think a day is going okay, only to begin dry heaving for no reason in the middle of the afternoon. I guess the only good thing i get from reading this is learning there are others who are dealing with this. 🙁

  28. Avatar
    Deepak Sharma May 17, 2019

    What Causes Nausea or Vomiting?
    Motion sickness or seasickness.
    Early stages of pregnancy (nausea occurs in approximately 50%-90% of all pregnancies; vomiting in 25%-55%)
    Medication-induced vomiting.
    Intense pain.
    Emotional stress (such as fear)
    Gallbladder disease.
    Food poisoning.
    Infections (such as the “stomach flu”)Overeating
    A reaction to certain smells or odors
    Heart attack
    Concussion or brain injury
    Brain tumor
    Ulcers
    Some forms of cancer
    Bulimia or other psychological illnesses
    Gastroparesis or slow stomach emptying (a condition that can be seen in people with diabetes)
    Ingestion of toxins or excessive amounts of alcohol
    Bowel obstruction
    Appendicitis
    The causes of vomiting differ according to age. For children, it is common for vomiting to occur from a viral infection, food poisoning, milk allergy, motion sickness, overeating or feeding, coughing, or blocked intestines and illnesses in which the child has a high fever. The timing of the nausea or vomiting can indicate the cause. When appearing shortly after a meal, nausea or vomiting may be caused by food poisoning, gastritis (inflammation of the stomach lining), an ulcer, or bulimia. Nausea or vomiting one to eight hours after a meal may also indicate food poisoning. However, certain food- borne bacteria, such as salmonella, can take longer to produce symptoms.
    Nausea is an uneasiness of the stomach that often comes before vomiting. Vomiting is the forcible voluntary or involuntary emptying (“throwing up”) of stomach contents through the mouth…(mygenericpharmacy)

  29. Avatar
    Donald Hutchins July 05, 2019

    I’ve been reading most of the posts that so many of you have made. It is unbelievable what is said by you all. I’ve been battling this for over 4 years. I’ve had the surgeries, the tests, I eat the Zofran constantly. I have a cardiologist, urologist, pain management, pulmonary and of course a primary care physician who have been on this journey with me. All of my doctors have had their own ideas and most of those ideas have been followed up on or acted upon. I really need some answers and I was wondering if any of you have experienced any positive results since your last posts. I have even pondered the possibility of contacting the TV program,”Mystery Diagnosis.” I pray that I will get some feedback from some or any of you ! I also hope that good and positive answers have came your way and that your prayers have been answered.

  30. Avatar
    Susie July 18, 2019

    7/18/19 Hi everyone,
    Current LPN. Current age 42. Started out with Fibromyalgia and Cholecystectomy (Gall bladder removal), N/V started just before Cholecystectomy. After the surgery I continued to have N/V and unable to eat normally for months at a time. Dropped almost 50#. Leveled out but still had nausea with occasional vomiting. Looked fantastic, felt horrible. Had EGD and gastric emptying done. 4 ulcers and gastroparesis. Had been taking Motrin intermittently with pain medications along with the standard Zofran and Promethazine since day 1 of N/V and 7 years later continue to be taking it. Started gaining weight but it was mostly swelling all over my body all throughout 2016-2018. At 9 month pregnancy weight. 192#. Not diabetic. Diagnosed with Stage IIB Cervical Cancer that had spread to surrounding tissue early 2018, chemo radiation treatments x6 weeks then Brachytherapy x6 weeks (HDR). Easily dehydrated now and make a trip to local ER for a bag or two when I get too hot or sweat too much bc the chemoradiation put me into instant menopause. I eat very very little yet still weigh in the 190’s. My hair didn’t fall out with the chemo but is falling out now after a MRI with Gadolinium to rule out brain cancer. Another EGD with slight irritation to esophagus. Gastric emptying test coming up next month along with colonoscopy. There has been little to no relief of the N/V throughout all of this. Reglan did help for a small amount of time after 1st EGD but it cannot be taken long term. It is very tough to lead a normal life and my life has not been normal since my Cholecystectomy. I will post follow up next month for the 2nd gastric emptying and colonoscopy. I do have HTN and increased anxiety most of my entire life. I wish for the same answers that all on here do. I wish for a normal life. I am single right now so that’s one less stressor. I’m so sorry for those on here suffering as I am as well so I do understand. Including enough to understand missing days off work, urinating with extreme N/V. I hope to find out more soon. There has to be a reason and a way to fix or manage this disease that is preventing leading healthy normal lives. Thank you for listening.

  31. Avatar
    Marie August 09, 2019

    I to have been suffering with this condition only I have had it for more than 30 years without any kind of a diagnosis. It started out with vomiting a few times a year. Then it progressed to a few times a month and gradually has increased up to every couple of days. There is no warning. It just comes. One time I was driving in traffic and I threw up all over myself. Other times I was eating out and as I was leaving the wrenching started and I made it to the front door and got sick all over the entrance. Another time I was leaving a restaurant and immediately upon going thru door I got sick on my daughter. I will be sitting watching tv and it will start. I keep a throw up bag nearby. Tests thru the moon shows nothing . My only consolation is that I have had it for so long that if it was something serious I’d be dead by now. Never the less I can’t take living like this. I’m on my 3rd gastro Dr . If any one finds a diagnosis please let me know.

    • Avatar
      Lori August 24, 2019

      I know what you mean. I throw up at least twice a week and it always starts out with huge gushes of whatever I last ate. Then I vomit clear brown a few times,then dry-heave. With each episode, I cthrow up seven or eight times until my stomach is empty. Two nights ago, I was vomiting so much, I started bringing up bile. My stomach is still unsettled . I’m like you. I keep a pail next to my bed, because sometimes it comes on so fast, I throw up all the floor.. This started with a stomach virus last winter where I couldn’t keep anything down. I’ve been given Zofran for the vomiting with limited success

    • Avatar
      Lori August 24, 2019

      I’m 27 years old and have had bouts of severe nausea and vomiting at least twice a week for the past two years. I start by throwing up everything I ate that day,then it turns to clear brown liquid,then dry-heaving painfully. I keep going until there is nothing left in my stomach.With each episode,I vomit seven or eight times. I have to keep a bedside pail. Thursday night, I threw up all night long,and yesterday morning,vomited bile. I have been given Zofran in the ER for the vomiting with limited success.

  32. Avatar
    Stephen Casper September 02, 2019

    I had rotator cuff surgery and when I was discharged they had me taking Opioids with NSAIDS. I ended up getting constipation for 4 days and then diverticulitis. I was taking daily aspirin as well. I am through with all of the above medications in my future. I will be taking Tylenol instead and also Turmeric.

  33. Avatar
    Kelly September 17, 2019

    I’m 47 years female and have been nauseous all day every day for the past 8 years. I dont vomit much. My nauseous is worse in the morning than the afternoon for the most part. Sometimes it’s just bad all day. I have no other symptoms. I just push through it because I have to. I’m glad I found this site to know there are others like me out there. I’m sorry you all are suffering. You’re in my prayers.

  34. Avatar
    Geistpuppe October 04, 2019

    I’ve been throwing up for almost 8 months every day. After a second opinion, they just prescribed buspirone for 30 days. It is an antianxiety med that can relax your GI. We will see. I already take Nexium, Pepcid and FD Guard. This is frustrating, especially when you have other health conditions that don’t have answers.

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