• Can Microbial Dysbiosis Cause Colonic Inflammation?

Can Microbial Dysbiosis Cause Colonic Inflammation?

Dysbiosis contributes to the pathogenesis of inflammatory bowel diseases (IBD) by altering colonic expression of genes that regulate inflammation and the immune response, researchers report in the July issue of Cellular and Molecular Gastroenterology and Hepatology. An altered intestinal microbiota composition has been associated with IBD. However, it is not

Read more
  • Genetic Variants Associated with IBD Alter Immune Regulatory Signals from Beneficial Microbes

Genetic Variants Associated with IBD Alter Immune Regulatory Signals from Beneficial Microbes

Polymorphisms in susceptibility genes appear to promote development of inflammatory bowel diseases (IBD) by altering the abilities of immune cells to sense protective signals from the microbiome, researchers report. These findings help fill the missing link between genetic risk variants for IBD and dysbiosis of the intestinal microbiome. More than

Read more