• Review: How Does the Tumor Stroma Contribute to Pancreatic Cancer Progression, and Can We Stop It?

Review: How Does the Tumor Stroma Contribute to Pancreatic Cancer Progression, and Can We Stop It?

Recently developed approaches for reshaping the pancreatic tumor stroma might be used in treatments for pancreatic cancer, according to a review in the March issue of Gastroenterology. The authors discuss relationships among the pancreatic tumor extracellular matrix, the vasculature, the immune system, and metabolism, and how these might be manipulated to stop pancreatic tumor

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  • Gut Microbiome Determines Efficacy of Cancer Immunotherapy

Gut Microbiome Determines Efficacy of Cancer Immunotherapy

Specific groups of intestinal microbes can boost the anti-tumor effects of cancer immunotherapies in mice, researchers show. Cancer immunotherapies that block immune inhibitory pathways have been tested in patients with several tumor types, but responses have varied. A study published in Science, while not the first to link gut microbes

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