• Special Issue: Genetics, Genetic Testing, and Biomarkers of Digestive Diseases

Special Issue: Genetics, Genetic Testing, and Biomarkers of Digestive Diseases

A special issue of Gastroenterology features 14 articles discussing the genetic factors that contribute to a range of gastrointestinal (GI),  hepatobiliary, and pancreatic diseases, and how this information can be used in diagnosis and treatment of patients. An introduction to the special issue explains the value of associating diseases with specific genetic variants, which can help

Read more

Are There Stem Cells in the Esophagus and Stomach?

Researchers have identified potential stem cells in human esophagus and stomach, as well as those in metaplastic esophagus that could lead to esophageal cancer, according to the April issue of Gastroenterology. Stem cells have been reported to exist in the basal layer of the human esophagus—their progeny are believed to

Read more

Can Proton Pump Inhibitors Prevent Esophageal Cancer?

Proton-pump inhibitor (PPI) therapy reduces risk of esophageal cancer in patients with Barrett’s esophagus (BE), according to the April issue of Clinical Gastroenterology and Hepatology. In BE, the squamous epithelium of the distal esophagus is replaced by metaplastic columnar epithelium, as a result of chronic exposure to stomach acid. Patients

Read more