• What are the Effects of Prednisolone in Patients With Severe Alcoholic Liver Disease?

What are the Effects of Prednisolone in Patients With Severe Alcoholic Liver Disease?

Infections are frequent in patients with severe alcoholic liver disease, but are only independently associated with mortality when patients receive prednisolone, researchers report in the April issue of Gastroenterology. This could offset prednisolone’s therapeutic benefit. This study’s senior author, Mark Thursz, discusses the findings in a video abstract. As with

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  • Finding Circulating Tumor Cells in Patients With Pancreaticobiliary Cancers

Finding Circulating Tumor Cells in Patients With Pancreaticobiliary Cancers

Circulating tumor cells (CTCs) can be isolated from portal venous blood collected during endoscopic ultrasound (EUS) of patients with pancreaticobiliary cancers, researchers report in the December issue of Gastroenterology. CTCs isolated from peripheral blood of patients with metastatic breast, colorectal, or prostate cancer can be analyzed to predict patient survival. However, blood samples from

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  • Special Issue: Genetics, Genetic Testing, and Biomarkers of Digestive Diseases

Special Issue: Genetics, Genetic Testing, and Biomarkers of Digestive Diseases

A special issue of Gastroenterology features 14 articles discussing the genetic factors that contribute to a range of gastrointestinal (GI),  hepatobiliary, and pancreatic diseases, and how this information can be used in diagnosis and treatment of patients. An introduction to the special issue explains the value of associating diseases with specific genetic variants, which can help

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  • Is Fecal Calprotectin a Good Marker of Crohn’s Disease Recurrence?

Is Fecal Calprotectin a Good Marker of Crohn’s Disease Recurrence?

The fecal concentration of calprotectin can be used to monitor for recurrence of Crohn’s disease, with a high enough negative predictive value that physicians can be confident they won’t miss patients with recurrent disease, researchers report in the May issue of Gastroenterology. Approximately 80% of patients with Crohn’s disease require surgery

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What Happens After Patients are Diagnosed With Celiac Disease?

Most patients with celiac disease are not adequately followed, according to the August issue of Clinical Gastroenterology and Hepatology (CGH). Improving follow-up strategies for patients with celiac disease could improve their outcomes. Adherence to a gluten-free diet is the only effective treatment for celiac disease. This is a difficult diet

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