• Do Different Bariatric Procedures Have Different Effects in Different Patients?

Do Different Bariatric Procedures Have Different Effects in Different Patients?

Different endoscopic and surgical procedures for weight-loss have different effects on gastric emptying that affect weight loss, researchers report in the January issue of Clinical Gastroenterology and Hepatology. Patients should therefore be assessed for gastric emptying of solids before therapy is selected. The study found that patients with rapid gastric

Read more
  • Is Red Wine Consumption Good for Your Intestinal Microbiome?

Is Red Wine Consumption Good for Your Intestinal Microbiome?

Consumption of red wine increases gut health, based on α-diversity of the intestinal microbiome, researchers report in the January 2020 issue of Gastroenterology. White wine had only weak effects, whereas beer, cider, spirits had none. The researchers propose that even infrequent red wine consumption benefits gut health, possibly via effects

Read more
  • What are the Risk Factors for Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes?

What are the Risk Factors for Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes?

Persons with type 2 diabetes have a more than 2-fold increase in risk for severe liver disease, researchers report in the December issue of Clinical Gastroenterology and Hepatology. The authors found risk factors that might be used to identify persons with type 2 diabetes who should be screened for liver disease.

Read more
  • Combined Genetic and Clinical Data Do Not Improve Determination of Risk for Esophageal Adenocarcinoma

Combined Genetic and Clinical Data Do Not Improve Determination of Risk for Esophageal Adenocarcinoma

Addition of genetic information to clinical factors does not increase identification of individuals at risk for esophageal adenocarcinoma, researchers report in the January 2019 issue of Gastroenterology. New screening and risk evaluation methods are needed to improve early detection of esophageal adenocarcinoma, because most patients receive a diagnosis at a late

Read more
  • What Endoscopic Techniques are Available for Weight Loss?

What Endoscopic Techniques are Available for Weight Loss?

Endoscopic techniques have been approved by the FDA for management of obesity, with many new devices and technologies in development. The pros and cons of these approaches, and the questions to be answered, are covered in a review article by Andrew C. Storm et al in the November issue of Clinical

Read more
  • Efficacy of Endoscopic Sleeve Gastroplasty In Reducing Body Weight and Metabolic Complications

Efficacy of Endoscopic Sleeve Gastroplasty In Reducing Body Weight and Metabolic Complications

Endoscopic sleeve gastroplasty (ESG) sustains loss of total body weight for up to 24 months, and also reduces markers of hypertension, diabetes, and hypertriglyceridemia, researchers report from a prospective study published in the April issue of Clinical Gastroenterology and Hepatology. ESG is an incisionless, minimally invasive bariatric procedure that reduces the

Read more
  • A Minimally Invasive Endoscopic Procedure Instead of Bariatric Surgery?

A Minimally Invasive Endoscopic Procedure Instead of Bariatric Surgery?

Endoscopic sleeve gastroplasty (ESG) delays gastric emptying, induces early satiation, and significantly reduces body weight, researchers report in the January issue of Clinical Gastroenterology and Hepatology. ESG could therefore be an alternative to bariatric surgery for some patients with obesity. Although bariatric surgery is the most effective therapy for obesity,

Read more
  • How Much Do Antibiotics Increase Risk of Obesity in Young Children?

How Much Do Antibiotics Increase Risk of Obesity in Young Children?

Administration of 3 or more courses of antibiotics to children younger than 2 years greatly increases their risk for early childhood obesity, researchers report in the July issue of Gastroenterology. Antibiotics have been used to promote weight gain in the agricultural industry for decades. This effect is believed to be

Read more

Obesity Appears to Contribute to Increasing Use of Prescription Drugs

Prescription drug use in the United States increased by 8% over a 10 year period, and users of 5 or more prescription drugs almost doubled. Increases in prescriptions for specific agents appears to reflect the growing need for treatment of complications associated with the increase in overweight and obesity. The

Read more
  • Leptin Mutation Causes Early-Onset Extreme Obesity

Leptin Mutation Causes Early-Onset Extreme Obesity

A mutation in the gene encoding the appetite-controlling hormone leptin (LEP) found to cause extreme obesity in a young child, researchers report. Martin Wabitsch et al describe insatiable appetite and early-onset extreme obesity in a 2-year old caused by a homozygous transversion in LEP.  The boy had a high serum

Read more