• Efficacy of Endoscopic Sleeve Gastroplasty In Reducing Body Weight and Metabolic Complications

Efficacy of Endoscopic Sleeve Gastroplasty In Reducing Body Weight and Metabolic Complications

Endoscopic sleeve gastroplasty (ESG) sustains loss of total body weight for up to 24 months, and also reduces markers of hypertension, diabetes, and hypertriglyceridemia, researchers report from a prospective study published in the April issue of Clinical Gastroenterology and Hepatology. ESG is an incisionless, minimally invasive bariatric procedure that reduces the

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  • A Minimally Invasive Endoscopic Procedure Instead of Bariatric Surgery?

A Minimally Invasive Endoscopic Procedure Instead of Bariatric Surgery?

Endoscopic sleeve gastroplasty (ESG) delays gastric emptying, induces early satiation, and significantly reduces body weight, researchers report in the January issue of Clinical Gastroenterology and Hepatology. ESG could therefore be an alternative to bariatric surgery for some patients with obesity. Although bariatric surgery is the most effective therapy for obesity,

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  • How Much Do Antibiotics Increase Risk of Obesity in Young Children?

How Much Do Antibiotics Increase Risk of Obesity in Young Children?

Administration of 3 or more courses of antibiotics to children younger than 2 years greatly increases their risk for early childhood obesity, researchers report in the July issue of Gastroenterology. Antibiotics have been used to promote weight gain in the agricultural industry for decades. This effect is believed to be

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Obesity Appears to Contribute to Increasing Use of Prescription Drugs

Prescription drug use in the United States increased by 8% over a 10 year period, and users of 5 or more prescription drugs almost doubled. Increases in prescriptions for specific agents appears to reflect the growing need for treatment of complications associated with the increase in overweight and obesity. The

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  • Leptin Mutation Causes Early-Onset Extreme Obesity

Leptin Mutation Causes Early-Onset Extreme Obesity

A mutation in the gene encoding the appetite-controlling hormone leptin (LEP) found to cause extreme obesity in a young child, researchers report. Martin Wabitsch et al describe insatiable appetite and early-onset extreme obesity in a 2-year old caused by a homozygous transversion in LEP.  The boy had a high serum

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How Can We Prevent Pancreatic Disease?

Tobacco use, obesity, and heavy use of alcohol are the factors most likely to increase risk for pancreatic diseases, researchers report in the October issue of Clinical Gastroenterology and Hepatology. Vegetables and fruit, on the other hand, appear to reduce risk. Strategies to prevent acute pancreatitis, chronic pancreatitis, and pancreatic

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FDA Approves New Obesity Drug

The US Food and Drug Administration (FDA) approved the third new prescription drug for obesity since 2012. The drug, Contrave, to be used along with a low-calorie diet and exercise regimen, was approved for treatment of obese adults (body mass index [BMI] of 30 or greater) or overweight adults (BMI

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