• Can a Cocktail Prevent Colorectal Adenoma Recurrence?

Can a Cocktail Prevent Colorectal Adenoma Recurrence?

The combination of calcitriol, aspirin, and calcium carbonate did not prevent recurrence of colorectal adenomas over a 3-year period, found a prospective study published in the January issue of Gastroenterology. This negative result might have been affected by the numbers of smokers included in the study or low doses of

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  • Expert Panel Recommends Aspirin Therapy for Prevention of Colorectal Cancer

Expert Panel Recommends Aspirin Therapy for Prevention of Colorectal Cancer

For the first time, an expert panel has recommended aspirin therapy to prevent not only heart attacks but also colorectal cancer. The guideline for those at high risk of heart disease, published September 14 in a draft report from the US Preventive Services Task Force is the first time a major

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Can Proton Pump Inhibitors Prevent Esophageal Cancer?

Proton-pump inhibitor (PPI) therapy reduces risk of esophageal cancer in patients with Barrett’s esophagus (BE), according to the April issue of Clinical Gastroenterology and Hepatology. In BE, the squamous epithelium of the distal esophagus is replaced by metaplastic columnar epithelium, as a result of chronic exposure to stomach acid. Patients

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How Does Aspirin Prevent Cancer?

Aspirin blocks proliferation of colorectal cancer cells and causes them to self destruct by inhibiting the mechanistic target of rapamycin (mTOR), according to the June issue of Gastroenterology. Aspirin is a nonsteroidal anti-inflammatory drug that has been shown in many studies to reduce risk of cancer—particularly of CRC—by unknown mechanisms.

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Anti-Inflammatory Drugs Prevent Colorectal Cancer (for Some)

Aspirin and other anti-inflammatory drugs prevent colorectal cancer (CRC) in some people but not others, according to the March issue of Gastroenterology. Andrew Chan et al. found that these drugs reduce the risk of CRC only in women with high levels of soluble tumor necrosis factor receptor 2 (sTNFR-2), a

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