• Effects of Diet, Intestinal Inflammation, and the Microbiome on Risk of Colorectal Cancer

Effects of Diet, Intestinal Inflammation, and the Microbiome on Risk of Colorectal Cancer

Diets that promote intestinal inflammation can increase risk of colorectal carcinomas associated with specific bacteria in the microbiome, researchers report in the October issue of Clinical Gastroenterology and Hepatology. Diet-induced intestinal inflammation alters the gut microbiome to contribute to colorectal cancer risk, which might be reduced with dietary changes. Chronic inflammation

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  • Does Drinking Coffee Increase Survival of Patients With Colorectal Cancer?

Does Drinking Coffee Increase Survival of Patients With Colorectal Cancer?

Drinking 2 or more cups of coffee per day after a diagnosis of stage I to III colorectal cancer (CRC) reduces risk of CRC-specific and all-cause mortality, researchers report in the March issue of Gastroenterology. Patients who maintain a high level of coffee consumption before and after diagnosis have even better odds for survival.

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  • Does Coffee Affect Development of Cholestatic Liver Disorders?

Does Coffee Affect Development of Cholestatic Liver Disorders?

Lower levels of coffee consumption are associated with primary sclerosing cholangitis (PSC), but not primary biliary cirrhosis (PBC), researchers report in the September issue of Clinical Gastroenterology and Hepatology. Coffee is considered to be a medically beneficial beverage—consumption has been associated with reductions in metabolic syndrome, cardiovascular disease, and weight

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Coffee, Beyond Caffeine

Coffee—caffeinated or decaffeinated—protects liver and gastrointestinal cells from toxic compounds, according to Sandra Kalthoff et al. in the November issue of Gastroenterology. In many epidemiology studies, coffee consumption reduced the risk of inflammation, chronic liver diseases, hepatocellular carcinoma (HCC), and other GI disorders. Its mechanisms are unclear, however, because coffee

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