• Expert Panel Recommends Aspirin Therapy for Prevention of Colorectal Cancer

Expert Panel Recommends Aspirin Therapy for Prevention of Colorectal Cancer

For the first time, an expert panel has recommended aspirin therapy to prevent not only heart attacks but also colorectal cancer. The guideline for those at high risk of heart disease, published September 14 in a draft report from the US Preventive Services Task Force is the first time a major

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  • How do Differentiated Tumor Cells Support Cancer Stem Cells?

How do Differentiated Tumor Cells Support Cancer Stem Cells?

Differentiated colorectal cells produce stem cell factor (SCF) to activate KIT signaling in tumor-initiating cells, researchers report in the September issue of Gastroenterology. This pathway maintains the stem-like features of these tumor cells, predominantly under conditions of hypoxia. Colorectal tumors are organized hierarchically and their growth is mediated by an

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  • Can Capsule Colonoscopy Accurately Detect Polyps and Adenomas?

Can Capsule Colonoscopy Accurately Detect Polyps and Adenomas?

In an average-risk screening population, capsule colonoscopy identified individuals with polyps and adenomas with high levels of specificity, researchers report in the May issue of Gastroenterology. This procedure might be useful for patients who cannot undergo colonoscopy or who had incomplete colonoscopies. Capsule endoscopy, which involves an ingestible pill-sized endoscope that

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  • Special Issue: Food, the Immune System, and the GI Tract

Special Issue: Food, the Immune System, and the GI Tract

The digestion of food and absorption of nutrients is the principal role of the gastrointestinal (GI) tract—everyone wants to know what we should eat and how it affects our body. Interactions between food and the immune system affect our microbiome, development of food allergies, nutrition, risk for inflammatory disorders or cancer, and even

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What are the Barriers to CRC Screening?

Waiving copayments for colonoscopy examinations to detect colorectal cancer (CRC) increases the number of patients that undergo screening, according to a study published in the July issue of Clinical Gastroenterology and Hepatology. Colonoscopy is a recommended, cost-effective method of CRC screening that appears to reduce mortality, yet only half of

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