• Can Direct-acting Antivirals Treatment of HCV Reactivate Herpesvirus Infection?

Can Direct-acting Antivirals Treatment of HCV Reactivate Herpesvirus Infection?

Researchers report reactivation of herpesvirus in 10 patients with hepatitis C virus (HCV) infection treated with direct-acting antiviral (DAA) agents in the November issue of Clincial Gastroenterology and Hepatology. Christie Perelló et al performed a case series analysis of reactivation of herpesvirus in patients with HCV infection treated with DAA

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Pyoderma Gangrenosum in Fingers of Patient With Crohn’s Disease

In the July issue of Clinical Gastroenterology and Hepatology, researchers describe a patient with Crohn’s disease who developed pyoderma gangrenosum in an unusual location. Faisal Inayat and Abu Hurairah describe a 40-year-old woman who came into the hospital with bilateral, mild, localized pain and discoloration of the fingernails for 10 days (see picture).

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  • Study Estimates Medical Errors May Cause More Than 250,000 Deaths Each Year in the US

Study Estimates Medical Errors May Cause More Than 250,000 Deaths Each Year in the US

Medical error is the third leading cause of death in the United States, after heart disease and cancer, a study concluded. Analyzing medical death rate data over an 8 year period, Marin Makary and Michael Daniel (Johns Hopkins University [JHU]) estimated that more than 250,000 deaths/year are due to medical error

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  • 5 Hospitalized and 1 Dead in Clinical Trial in France

5 Hospitalized and 1 Dead in Clinical Trial in France

Five men were hospitalized and 1 died after a drug trial in France, the country’s health minister announced on January 15. Marisol Touraine, the minister for social affairs, health, and women’s rights, said in a statement that her office was informed the evening of January 14 about a “serious accident”

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  • Should Patients Undergo Endoscopic Sphincterotomy Before Receiving Self-expandable Metallic Stents?

Should Patients Undergo Endoscopic Sphincterotomy Before Receiving Self-expandable Metallic Stents?

Endoscopic sphincterotomy (ES) provides no benefit to patients receiving self-expandable metallic stents (SEMS) for a biliary stricture caused by pancreatic cancer, researchers report in the June issue of Clinical Gastroenterology and Hepatology. The randomized controlled trial showed that ES procedure did not affect number of adverse events, SEMS patency, or

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  • What are the Effects of Antiviral Therapy in Patients With IBD and CMV Infection?

What are the Effects of Antiviral Therapy in Patients With IBD and CMV Infection?

Cytomegalovirus (CMV) infection complicates inflammatory bowel disease (IBD), but anti-viral therapy reduces the need for bowel surgery, researchers report in the May issue of Clinical Gastroenterology and Hepatology. The benefits of anti-viral treatment are greatest for patients with high-grade disease, they show. CMV infection is more common in patients with

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  • What’s Wrong With Herbal Supplements?

What’s Wrong With Herbal Supplements?

Herbal supplements, used by many people for weight loss and bodybuilding purposes but also to improve well-being and reduce symptoms of chronic diseases, have recently come under investigation because of uncertainty about their contents, safety, and efficacy. On February 3, the New York Times wrote that the New York State attorney general’s office accused 4 major retailers of selling

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  • Video: Which Patients with Crohn’s Disease Need a CT Scan?

Video: Which Patients with Crohn’s Disease Need a CT Scan?

Researchers have developed a system to identify patients with Crohn’s disease who do not require computed tomography (CT) evaluation, described by Shail M. Govani et al  in the October issue of Clinical Gastroenterology and Hepatology. The system uses laboratory test results to avoid CT analysis, and thereby unnecessary exposure to radiation and increased cancer risk. People who come to the emergency department with

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Do Continuous-flow Left Ventricular Assist Devices Increase Risk of GI Bleeding and Thrombosis?

Continuous-flow left ventricular assist devices increase the risk of gastrointestinal (GI) bleeding and thromboembolic events, researchers report in the September issue of Clinical Gastroenterology and Hepatology. Left ventricular assist device (LVAD) implantation results in improved survival and quality of life in patients with advanced heart failure. Continuous-flow LVADs (CF-LVADs) are

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Are IBD Drugs Safe During Pregnancy?

Researchers find no evidence that inflammatory bowel disease (IBD) during pregnancy, or medical treatment for IBD during pregnancy, increases risk for congenital abnormalities in children. The findings, based on a large database analysis, are published in the January issue of Gastroenterology. IBD frequently affects women of reproductive age, and is often

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