• Does Mucosal Healing Mean Transmural Healing in Children With Crohn’s Disease?

Does Mucosal Healing Mean Transmural Healing in Children With Crohn’s Disease?

 One-third of children with Crohn’s disease have healing in only the mucosa or the bowel wall (not both), researchers report in the July issue of Clinical Gastroenterology and Hepatology. Levels of fecal calprotectin below 300 μg/identify children with mucosal healing. In patients with CD, mucosal healing is associated with reduced risk of relapse,

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  • Can we Identify People With IBD Before Symptoms Develop?

Can we Identify People With IBD Before Symptoms Develop?

People have high plasma levels of interleukin-6 (IL6) and c-reactive protein years before they are diagnosed with inflammatory bowel diseases (IBD), researchers report in the June issue of Clinical Gastroenterology and Hepatology. These markers of systemic inflammation could be features of early-stage disease used to identify patients at risk. Crohn’s

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  • Is Fecal Calprotectin a Good Marker of Crohn’s Disease Recurrence?

Is Fecal Calprotectin a Good Marker of Crohn’s Disease Recurrence?

The fecal concentration of calprotectin can be used to monitor for recurrence of Crohn’s disease, with a high enough negative predictive value that physicians can be confident they won’t miss patients with recurrent disease, researchers report in the May issue of Gastroenterology. Approximately 80% of patients with Crohn’s disease require surgery

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