• Candy Cane Esophagus From Hot Tea

Candy Cane Esophagus From Hot Tea

Researchers describe a patient with a “candy cane appearance” of the esophagus, due to acute thermal injury, in the October issue of Clinical Gastroenterology and Hepatology. Upon further investigation, the authors found that the patient had poured hot boiling tea into his throat. Arun AC and Jenish Rajma describe the case of a 19-year-old

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  • What is the Best Treatment for Severe Alcoholic Hepatitis?

What is the Best Treatment for Severe Alcoholic Hepatitis?

Corticosteroids, alone or in combination with pentoxifylline or N-acetylcysteine (NAC), reduce short-term mortality in patients with severe alcoholic hepatitis, a meta-analysis shows in the October issue of Gastroenterology. However, there is no treatment to reduce medium-term mortality, the authors find. Severe alcoholic hepatitis is characterized by progressive inflammatory injury to hepatocytes and

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  • Author Q and A Series: Alcohol, the Microbiota, and Liver Disease

Author Q and A Series: Alcohol, the Microbiota, and Liver Disease

Chronic alcohol consumption disrupts the intestinal microbiota to reduce production of saturated long-chain fatty acids and subsequently the proportion and functions of hepatoprotective lactobacilli, Peng Chen et al report in the January issue of Gastroenterology. Dietary approaches to restore levels of saturated fatty acids in the intestine might therefore reduce ethanol-induced liver injury in patients with

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  • What is the Best Way to Care for Patients with Alcoholic Hepatitis?

What is the Best Way to Care for Patients with Alcoholic Hepatitis?

Although alcohol-related liver disease is the 8th most common cause of mortality in the US and the 2nd leading cause of mortality among all gastrointestinal diseases, there are few therapeutic options for patients or resources to support identification of new therapies. However, treatment approaches are being developed; a review in

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