How Might Carbonation Contribute to Obesity?

Carbonation makes drinks seem less sweet than they really are, and could increase consumption of sugar and food, neuroscientists report in the September issue of Gastroenterology. It might be therefore be best for weight-loss plans to avoid carbonated beverages. Addition of carbon dioxide (CO2) to water (carbonation) makes it effervescent

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  • Overall Diet, Rather than Specific Foods, Affect Risk for Esophageal Cancer

Overall Diet, Rather than Specific Foods, Affect Risk for Esophageal Cancer

A Mediterranean diet and overall healthy eating, rather than a particular group of foods or nutrients, reduce the risk for esophageal cancers—particularly esophageal squamous cell carcinoma (ESCC), according to the September issue of Clinical Gastroenterology and Hepatology. Although diet has been associated with cancers of the esophagus and stomach, few prospective

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  • Is Gluten the Culprit in Non-Celiac Gluten Sensitivity?

Is Gluten the Culprit in Non-Celiac Gluten Sensitivity?

Rapidly fermented poorly absorbed short-chain carbohydrates, rather than gluten or other wheat proteins, might cause gastrointestinal symptoms in people who do not have celiac disease but feel better on gluten-free diets, according to the August issue of Gastroenterology. Individuals with non-celiac gluten sensitivity (NCGS), do not have celiac disease (based on

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Molecular Mechanisms of Roux-en-Y Gastric Bypass

Many of the beneficial effects of Roux-en-Y gastric bypass (RYGB), including improved glucose homeostasis, require the actions of melanocortin-4 receptors (MC4Rs) on autonomic neurons, according to the March issue of Gastroenterology. Fasting glycemia often improves within days of RYGB (see below figure), which produces greater improvements in glucose homeostasis than

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Does Vitamin D Prevent Crohn’s Disease?

Women with higher intake of vitamin D are less likely to develop Crohn’s disease or ulcerative colitis, according to a study published in the March issue of Gastroenterology. Vitamin D deficiency has been described in patients with inflammatory bowel diseases (IBD), and administration of vitamin D to mice with colitis

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How Do Lipids Affect Liver Disease?

Changes in lipid intake or metabolism can affect development of liver injury and fibrosis, according to two studies in mice published in the January issue of Gastroenterology. The liver is an important site of energy production and lipid metabolism. However, accumulation of excess fat in the liver promotes development of fibrosis, cirrhosis

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Does Celiac Disease Increase the Risk of GI Cancer?

People with celiac disease do not have an increased risk of developing gastrointestinal (GI) cancers, according to a large population-based study from Peter Elfström et al. in the January issue of Clinical Gastroenterology and Hepatology. Celiac disease has been associated with GI cancers in small studies, but there have been

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Coffee Therapy for Hepatitis C?

Drinking 3 cups of coffee a day helps patients with hepatitis C respond to treatment, report Neal Freedman et al. in the June issue of Gastroenterology. Coffee reduces risks of progression of liver diseases and risk for hepatocellular carcinoma, so Freedman et al. investigated whether it also had benefits for patients

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