• Developing a New Combination Treatment for HBV Infection

Developing a New Combination Treatment for HBV Infection

NVR3–778, a capsid assembly modulator, reduces serum levels of hepatitis B virus (HBV) DNA and HBV RNA in mice with humanized livers and stable HBV infection, researchers report in the February issue of Gastroenterology. The combination of NVR3–778 and interferon prevented viral replication and HBV RNA particle production to a greater extent than

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  • What is the Best Treatment Strategy for Hepatitis B?

What is the Best Treatment Strategy for Hepatitis B?

Response-guided interferon therapy is the most cost-effective first-line treatment for hepatitis B e antigen (HBeAg)-positive patients, whereas nucleos(t)ide analogues are the most cost-effective first-line therapy for HBeAg-negative patients, researchers report in the February issue of Clinical Gastroenterology and Hepatology. Pegylated interferon and nucleos(t)ide analogues are recommended first-line treatment options for

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Advance Against Hepatitis B

Long-term treatment with entecavir, an inhibitor of hepatitis B virus (HBV) replication, reduces cirrhosis and fibrosis in patients with chronic hepatitis B infection, report Eugene Schiff et al. in the March issue of Clinical Gastroenterology and Hepatology.  Patients with chronic hepatitis B can develop liver fibrosis or cirrhosis and have

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