• What Changes Occur in the Esophageal Epithelial Barrier During Disease Development?

What Changes Occur in the Esophageal Epithelial Barrier During Disease Development?

A review article in the May issue of Clinical Gastroenterology and Hepatology discusses esophageal epithelial barrier structure and function, new and old techniques for studying this barrier, and changes that occur during development of esophageal diseases. To identify mechanisms of diseases associated with barrier dysfunction, such as gastroesophageal reflux disease (GERD), eosinophilic esophagitis,

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Video: Prick Test to Identify Allergens That Cause Esophageal Sensitization

An esophageal prick test, in which allergens are injected directly into the esophageal mucosa, appears to identify individuals with esophageal sensitization, researchers report in the January issue of Gastroenterology. In patients with eosinophilic esophagitis (EoE), food allergens are believed to induce an inflammatory response that can make swallowing and eating a challenge. Identifying and

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  • Do Symptoms of Eosinophilic Esophagitis Indicate Disease Activity?

Do Symptoms of Eosinophilic Esophagitis Indicate Disease Activity?

Lack of symptoms of eosinophilic esophagitis (EoE) does not necessarily mean a lack of disease activity, researchers report in the March issue of Gastroenterology. They found only a moderate association between symptom scores and endoscopic or histologic features of remission. EoE is a chronic, immune- or antigen-mediated esophageal disease characterized

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  • Can Dietary Changes Reduce Eosinophilic Esophagitis in Adults?

Can Dietary Changes Reduce Eosinophilic Esophagitis in Adults?

Dietary elimination is a successful treatment approach for adults with eosinophilic esophagitis (EoE), researchers report in the August issue of Clinical Gastroenterology and Hepatology. EoE is characterized by inflammation or swelling of the esophagus associated with infiltration of eosinophils. Aeroallergens and food allergens might be involved in pathogenesis. Dietary elimination therapy has

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How Many People Have Eosinophilic Esophagitis?

Eosinophilic esophagitis (EoE), which was barely recognized 20 years ago, affects at least 150,000 people in the United States, with three-quarters being adults, report Evan Dellon et al. in the April issue of Clinical Gastroenterology and Hepatology. EoE, also known as allergic esophagitis, is an allergic inflammatory disease characterized by

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Eosinophilic Esophagitis? Change Your Diet.

Eliminating specific foods from your diet can reduce symptoms of eosinophilic esophagitis (EoE), according to the June issue of Gastroenterology. EoE is an immune disorder in which eosinophils cause inflammation of the esophagus, leading to difficulty swallowing and food impactions. Many adults cope for years with swallowing difficulties and do

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