Are All Patients With IBD at Increased Risk for Colorectal Cancer?

Although inflammatory bowel disease (IBD) increases risk for colorectal cancer (CRC), the risk is only substantial among patients with long-term, extensive colitis. Furthermore, CRC risk is reduced by thiopurine therapy, according to the July issue of Gastroenterology. Laurent Beaugerie et al. collected data from 19,486 patients with IBD (60% with

Read more

Differences in HCV Infection, and Effects of Treatment, Among Countries

Hepatitis C virus (HCV) infections have developed and spread at different rates in different countries, affecting outcomes of therapy, according to the October issue of Gastroenterology. Specific details of each population must therefore be considered in designing prevention and treatment programs. Although there are many treatment options for HCV infection,

Read more

What are the Barriers to CRC Screening?

Waiving copayments for colonoscopy examinations to detect colorectal cancer (CRC) increases the number of patients that undergo screening, according to a study published in the July issue of Clinical Gastroenterology and Hepatology. Colonoscopy is a recommended, cost-effective method of CRC screening that appears to reduce mortality, yet only half of

Read more

Many Patients Without GERD Continue to Take PPIs

More than 42% of patients with negative results from pH monitoring studies continue proton pump inhibitor (PPI) therapy, despite evidence that they do not have gastroesophageal reflux disease (GERD), according to the June issue of Clinical Gastroenterology and Hepatology. PPI therapy is effective for about 75% of patients with GERD

Read more

Does Vitamin D Prevent Crohn’s Disease?

Women with higher intake of vitamin D are less likely to develop Crohn’s disease or ulcerative colitis, according to a study published in the March issue of Gastroenterology. Vitamin D deficiency has been described in patients with inflammatory bowel diseases (IBD), and administration of vitamin D to mice with colitis

Read more

Does Celiac Disease Increase the Risk of GI Cancer?

People with celiac disease do not have an increased risk of developing gastrointestinal (GI) cancers, according to a large population-based study from Peter Elfström et al. in the January issue of Clinical Gastroenterology and Hepatology. Celiac disease has been associated with GI cancers in small studies, but there have been

Read more

As Incidence of HCV Infection Increases, a New Mouse Model to Study

The incidence of hepatitis C virus (HCV) infection and its complications—hepatocellular carcinoma (HCC) and cirrhosis—are increasing, according to Fasiha Kanwal et al. Fortunately, a new mouse model has been created to study disease progression and treatment, as described by Michael Washburn et al. These findings were reported in separate articles

Read more