• Using High-resolution Microendoscopy to Detect Gastrointestinal Neoplasia

Using High-resolution Microendoscopy to Detect Gastrointestinal Neoplasia

The high-resolution microendoscope (HRME) allows for real-time imaging of the esophageal and gastric epithelium with subcellular resolution. In an Advances in Translational Science article in the November issue of Clinical Gastroenterology and Hepatology, Justin S. Louie et al discuss the performance of this portable, low cost, optical biopsy technology in screening and surveillance of gastrointestinal

Read more

Researchers Characterize 4 Molecular Subtypes of Gastric Cancer

Stomach cancers fall into 4 distinct molecular subtypes, researchers report. This information could lead to new strategies to treat patients with specific types of gastric cancer. In the study, published online July 23, 2014, in Nature, researchers with The Cancer Genome Atlas Network (TCGA) report findings that could change how

Read more

Could Bone Marrow Cells Contribute to Stomach Cancer?

H pylori recruit bone marrow-derived cells to the gastric mucosa that contribute to tumor development, according to the February issue of Gastroenterology. H pylori infection promotes gastric carcinogenesis through many mechanisms, such as causing inflammation and producing virulence factors that alter gastric cell activity. Over time, these lead to metaplasia, dysplasia,

Read more