• Are Prebiotics or Diets Low in FODMAPs Better for Patients With Functional GI Disorders?

Are Prebiotics or Diets Low in FODMAPs Better for Patients With Functional GI Disorders?

Intermittent administration of prebiotics might be an alternative to dietary restrictions for patients with functional gut symptoms, researchers report in the October issue of Gastroenterology. A diet low in fermentable oligo-, di-, mono-saccharides and polyols (low-FODMAP diet) reduces symptoms of irritable bowel syndrome (IBS), and patients with gas-related symptoms can significantly

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  • What are the Effects of Anticoagulants in Patients With Cirrhosis and Portal Vein Thrombosis?

What are the Effects of Anticoagulants in Patients With Cirrhosis and Portal Vein Thrombosis?

Vitamin K antagonists (VKAs) increase risk of minor bleeding in patients with cirrhosis given anticoagulants for portal vein thrombosis (PVT), compared to patients without cirrhosis given VKAs, researchers report in the July issue of Clinical Gastroenterology and Hepatology. However, this risk is offset by the ability of VKA to increase portal

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  • What Comes First — the Psychological Disorder or the Gastrointestinal Disorder?

What Comes First — the Psychological Disorder or the Gastrointestinal Disorder?

More patients receive a diagnosis of a mood or anxiety disorder before diagnosis of a functional gastrointestinal disorder (FGID), researchers report in the July issue of Clinical Gastroenterology and Hepatology. The findings indicate opportunities for prevention and support the role of adverse socioeconomic factors in development of FGIDs in patients

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  • Gastroduodenal Metastases from Melanoma

Gastroduodenal Metastases from Melanoma

Researchers describe a case of gastroduodenal metastases from cutaneous melanoma, in the May issue of Gastroenterology. Inês Pita et al present the case of a 76-year-old man who arrived at the emergency department with exertional dyspnea and melena for the past 3 weeks, and an episode of presyncope. He denied orthopnea, paroxysmal nocturnal dyspnea,

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  • Hemosuccus Pancreaticus Caused by a Pancreatic Tumor

Hemosuccus Pancreaticus Caused by a Pancreatic Tumor

Researchers describe a rare cause of hemosuccus pancreaticus in a patient with pancreatic cancer. The gastrointestinal bleeding was caused by erosion of pancreatic adenocarcinoma into the colon, they show in the April issue of Clinical Gastroenterology and Hepatology. Hemosuccus pancreaticus is defined as hemorrhage from the ampulla of Vater via the pancreatic

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  • Can Yoga Reduce Symptoms of IBS?

Can Yoga Reduce Symptoms of IBS?

Yoga might be a feasible and safe adjunct treatment for irritable bowel syndrome (IBS), a systematic review shows in the December issue of Clinical Gastroenterology and Hepatology. The review found evidence for beneficial effects of yoga on gastrointestinal (GI) symptoms, quality of life, and anxiety, although further studies are needed. IBS is

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  • Video Abstract: Pros and Cons of Continued Aspirin Use in Patients with Lower GI Bleeding

Video Abstract: Pros and Cons of Continued Aspirin Use in Patients with Lower GI Bleeding

In aspirin users with a history of lower gastrointestinal bleeding, continued aspirin use increases risk of recurrent bleeding by almost 3-fold, but reduces risk of serious cardiovascular events by 40% and risk of death from other causes by 17%, researchers report in the August issue of Gastroenterology. First author Francis K.L. Chan discusses the group’s

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  • What can we do with Gastrointestinal Organoids?

What can we do with Gastrointestinal Organoids?

Researchers review the latest discoveries from studies of tissue-derived and pluripotent stem cell–derived intestinal, gastric, esophageal, liver, and pancreatic organoids in the May issue of Gastroenterology. Studies of organoids have provided valuable information about GI development, tissue homeostasis, and disease and might be used to develop personalized medicines. In vitro organoid cultures are

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  • Should All Patients with IBS be Screened for Celiac Disease?

Should All Patients with IBS be Screened for Celiac Disease?

Screening patients with irritable bowel syndrome (IBS) or other functional gastrointestinal disorders for celiac disease isn’t much more effective than screening the general population, researchers report in the November issue of Clinical Gastroenterology and Hepatology. Celiac disease produces symptoms similar to those of IBS, such as lower abdominal pain, diarrhea,

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  • VIDEO: Endoscopic Management of Gastrointestinal Leaks and Fistulae

VIDEO: Endoscopic Management of Gastrointestinal Leaks and Fistulae

Gastrointestinal leaks and fistulae can be serious acute complications or chronic conditions caused by inflammation, malignancy, or surgery. In a Perspective article in the October issue of Clinical Gastroenterology and Hepatology, Field F. Willingham and Jonathan M. Buscaglia discuss advanced endoscopic methods for less invasive treatment of these luminal defects. They explain that the main goal of

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