• How Does Estrogen Receptor Signaling Promote Growth of Liver Tumors?

How Does Estrogen Receptor Signaling Promote Growth of Liver Tumors?

The G-protein–coupled estrogen receptor (GPER1) is a hepatic sensor of estrogen that regulates liver growth during development, regeneration, and tumorigenesis, researchers show in a study of zebrafish and human liver published in the May issue of Gastroenterology. Inhibitors of GPER1 might be developed for liver cancer prevention or treatment. Liver cancer

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Does Menopause Affect Outcomes from Roux-en-Y Gastric Bypass Surgery?

Estradiol increases body weight loss and satiation effects of Roux-en-Y gastric bypass (RYGB) in ovariectomized rats, according to the August issue of Gastroenterology. Approximately ~85% of bariatric surgery procedures are performed on women, but little is known about the effects of menopause or reproductive hormones, such as estrogen, on outcomes.

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