• 3-D Imaging of T-cell Localization in Inflamed Colon Tissues

3-D Imaging of T-cell Localization in Inflamed Colon Tissues

Light sheet fluorescence microscopy (LSFM) provides accurate 3-dimensional images of inflammed intestine of mice with colitis, researchers show in a Gastroenterology in Motion article and video in the October issue of Gastroenterology. The authors demonstrate use of the technology to analyze migration of human T cells in colons of mice with colitis. Improved techniques are

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  • What is the Risk of Pancreatic Cancer in Patients with Low-Risk IPMNs?

What is the Risk of Pancreatic Cancer in Patients with Low-Risk IPMNs?

Low-risk intraductal papillary mucinous neoplasms have an almost 8% chance of progressing to pancreatic cancer within 10 years, whereas higher-risk IPMNs have almost 25% chance, reports a systematic review and meta-analysis in the October issue of Clinical Gastroenterology and Hepatology. Continued long-term surveillance is therefore important for patients with low-risk, as

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  • Video: EUS Detection of Early-stage Gastric Cancer in a Patient with FAP

Video: EUS Detection of Early-stage Gastric Cancer in a Patient with FAP

Endoscopic ultrasound (EUS) can detect early-stage gastric cancers developing beneath or within the mucosa that are not visualized by endoscopy in patients with familial adenomatous polyposis (FAP). Researchers report these findings along with a video in the August issue of Gastroenterology. FAP is a hereditary colorectal cancer syndrome characterized by colorectal polyps and colorectal cancer. Patients

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Gastrointestinal Bleeding Caused by Gastric Tuberculosis

Researchers describe a case of gastric tuberculosis that led to GI bleeding in the June issue of Clinical Gastroenterology and Hepatology. Vishal Sharma et al report that a 30-year-old man who was a resident of North India presented to emergency services with 2 episodes of painless hematemesis. He did not have a history of

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  • FUSE Outperforms Forward-viewing Colonoscopy in Detecting Dysplasia in Patients With IBD

FUSE Outperforms Forward-viewing Colonoscopy in Detecting Dysplasia in Patients With IBD

The panoramic views obtained with full-spectrum endoscopy (FUSE) increase the number of dysplastic lesions detected in the colon, compared with conventional forward-viewing colonoscopy, researchers report in the May issue of Gastroenterology. Inflammatory bowel diseases (IBDs) increase the risk of colorectal cancer. Surveillance colonoscopy with chromoendoscopy is recommended, but conventional forward-viewing colonoscopy

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  • What are the Most Accurate Non-invasive Techniques for Measuring Liver Fibrosis and Steatosis?

What are the Most Accurate Non-invasive Techniques for Measuring Liver Fibrosis and Steatosis?

Magnetic resonance elastography (MRE) is more accurate than transient elastography (TE) in identifying liver fibrosis of stage 1 or more, researchers report in the February issue of Gastroenterology, using biopsy analysis as the standard. They also show that MRI-based proton density fat fraction (MRI-PDFF) analysis is more accurate than TE-based

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  • Distinguishing a Pancreatic Pseudocyst from a Mucinous Cystic Neoplasm

Distinguishing a Pancreatic Pseudocyst from a Mucinous Cystic Neoplasm

Researchers describe the case of a patient with what appeared to be a pancreatic pseudocyst that was found to be a benign mucinous cystic neoplasm (MCN), based on analysis of a cyst wall biopsy. In the March issue of Gastroenterology, Katie Connor et al  describe a 22-year-old woman who came

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  • Who Should Undergo Surgery for Pancreatic Cysts?

Who Should Undergo Surgery for Pancreatic Cysts?

When should a patient with a pancreatic cystic lesion undergo surgery? How can we tell if the surgery will provide relief, or prevent death from pancreatic cancer, or burden a patient with an unnecessary procedure? Two articles in the October issue of Clinical Gastroenterology and Hepatology increase our understanding of

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  • A Quantitative Ultrasound Technology to Identify Patients with NAFLD and Quantify Steatohepatitis

A Quantitative Ultrasound Technology to Identify Patients with NAFLD and Quantify Steatohepatitis

A new quantitative ultrasound (QUS)  can accurately identify patients with non-alcoholic fatty liver disease (NAFLD) and quantify hepatic steatosis, researchers report in the July issue of Clinical Gastroenterology and Hepatology. With further validation, QUS could be an inexpensive, widely used technique to screen the general or at-risk population for NAFLD. The estimated prevalence of NAFLD

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  • Can Capsule Colonoscopy Accurately Detect Polyps and Adenomas?

Can Capsule Colonoscopy Accurately Detect Polyps and Adenomas?

In an average-risk screening population, capsule colonoscopy identified individuals with polyps and adenomas with high levels of specificity, researchers report in the May issue of Gastroenterology. This procedure might be useful for patients who cannot undergo colonoscopy or who had incomplete colonoscopies. Capsule endoscopy, which involves an ingestible pill-sized endoscope that

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