• What are the Long-Term Effects of Gastrointestinal Infections During Childhood?

What are the Long-Term Effects of Gastrointestinal Infections During Childhood?

An analysis of children affected by a Salmonella enteritidis outbreak more than 20 years ago provides evidence that pathogen-induced gastroenteritis during childhood is a risk factor for irritable bowel syndrome (IBS) in adults. The findings from this long-term study are published in the July issue of Gastroenterology. Functional dyspepsia and IBS affect

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Mapping HCV Infection in the Liver

Using single-cell laser capture and high-resolution analysis, researchers show that hepatitis C virus (HCV) infects hepatocytes in the human liver in nonrandom clusters, whereas expression of anti-viral molecules is scattered among hepatocytes. The findings are presented in the December issue of Gastroenterology. HCV predominantly infects hepatocytes, but most hepatocytes in

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How Dangerous Are H pylori-Negative Idiopathic Bleeding Ulcers?

Patients with a bleeding peptic ulcer not caused by Helicobacter pylori infection or non-steroidal anti-inflammatory drugs (NSAIDs) are at considerable risk of recurrent bleeding and death. Furthermore, acid-suppressive drugs do not protect these patients, according to the October issue of Clinical Gastroenterology and Hepatology. Peptic ulcers that are not associated

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Could Differences in Gut Bacteria Cause IBS?

The bacteria that reside in the intestines of adults and children with irritable bowel syndrome (IBS) differ from those of healthy adults and children, according to 2 studies in the November issue of Gastroenterology. Microorganisms account for 90% of the cells in our body (many cannot even be cultured); only

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H Pylori—Are They Gone Yet?

Helicobacter pylori infection can be treated with proton pump inhibitors (PPIs) and antibiotics, but physicians need ways to determine if the bacteria are completely eradicated months later. In the May issue of Clinical Gastroenterology and Hepatology, Luigi Gatta et al. describe a simple blood test that can detect H pylori

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