• How Is The Intestinal Microbiome Altered in Patients With IBD and Does it Change During Therapy?

How Is The Intestinal Microbiome Altered in Patients With IBD and Does it Change During Therapy?

Treatment of inflammatory bowel diseases (IBD) with anti-tumor necrosis factor (anti-TNF) drugs restores diversity to the intestinal microbiome, researchers report in the November issue of Gastroenterology.  The study associates metabolic interactions among luminal bacteria with outcomes of therapy. Altered interactions between the mucosal immune system and intestinal microbiota contribute to

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  • IBD Research Highlights from 2019 ECCO Congress

IBD Research Highlights from 2019 ECCO Congress

A variety of exciting findings from inflammatory bowel disease (IBD) research were presented at the Congress of the European Crohn’s and Colitis Organisation (ECCO), held in Copenhagen, March 7–9. Shixian Hu (Universitair Medisch Centrum Groningen, The Netherlands) reported on associations between genetic factors and the microbiome in patients with IBD.

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  • What Are the Best Endpoints for Trials of Agents for Ulcerative Colitis?

What Are the Best Endpoints for Trials of Agents for Ulcerative Colitis?

Despite advances in methods of clinical trials for ulcerative colitis (UC), there is still a large amount of variation in endpoints, even in definitions of response and remission, reseachers found in a systematic review published in the May issue of Clinical Gastroenterology and Hepatology. The authors conclude that we need a

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