• Video: EUS Detection of Early-stage Gastric Cancer in a Patient with FAP

Video: EUS Detection of Early-stage Gastric Cancer in a Patient with FAP

Endoscopic ultrasound (EUS) can detect early-stage gastric cancers developing beneath or within the mucosa that are not visualized by endoscopy in patients with familial adenomatous polyposis (FAP). Researchers report these findings along with a video in the August issue of Gastroenterology. FAP is a hereditary colorectal cancer syndrome characterized by colorectal polyps and colorectal cancer. Patients

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  • Do Patients Really Prefer Colon Capsule Endoscopy Over Colonoscopy?

Do Patients Really Prefer Colon Capsule Endoscopy Over Colonoscopy?

Slightly more than 50% of people with an inherited risk for colorectal cancer (CRC) agree to undergo screening for this cancer, and most prefer colonoscopy to colon capsule endoscopy—even though these are equally effective screening tools—researchers report in the December issue of Clinical Gastroenterology and Hepatology. Colonoscopy should therefore remain

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  • Special Issue: Genetics, Genetic Testing, and Biomarkers of Digestive Diseases

Special Issue: Genetics, Genetic Testing, and Biomarkers of Digestive Diseases

A special issue of Gastroenterology features 14 articles discussing the genetic factors that contribute to a range of gastrointestinal (GI),  hepatobiliary, and pancreatic diseases, and how this information can be used in diagnosis and treatment of patients. An introduction to the special issue explains the value of associating diseases with specific genetic variants, which can help

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  • What Gene Mutations Cause Familial Colorectal Cancers?

What Gene Mutations Cause Familial Colorectal Cancers?

Mutations in the DNA repair gene, FAN1, cause some inherited forms of colorectal cancer (CRC), researchers report in the September issue of Gastroenterology. Identification of another gene associated with this hereditary cancer will facilitate management of patients with family histories of cancer. Germline mutations in EPCAM, APC, MUTYH, POLE, POLD1, GREM1,

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What are the Risks for Relatives of Patients With Colorectal Cancer?

Close relatives of people with colorectal cancer (CRC) have a significant increase in prevalence of advanced neoplasms and should be screened for cancer, according to the March issue of Gastroenterology. Relatives of patients with CRC have been shown to be at increased risk for colorectal neoplasms, but little is known

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