What is Intrahepatic Cholangiocarcinoma?

Researchers have found that intrahepatic cholangiocarcinomas (ICCs) are really 2 different groups of tumors, based on molecular and genetic analyses, reported in the April issue of Gastroenterology. These findings identify class-specific mechanisms of oncogenesis that could lead to new treatment approaches for this common liver cancer. Cholangiocarcinoma is the second most

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Differences in HCV Infection, and Effects of Treatment, Among Countries

Hepatitis C virus (HCV) infections have developed and spread at different rates in different countries, affecting outcomes of therapy, according to the October issue of Gastroenterology. Specific details of each population must therefore be considered in designing prevention and treatment programs. Although there are many treatment options for HCV infection,

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An HIV Protein and Telomerase Inhibitor Join Forces Against Cancer

Researchers have found a way to specifically kill liver cancer cells and stop tumor growth. In the January issue of Gastroenterology, Guangming Chen et al. report that fusion of a natural inhibitor of telomerase to an HIV protein stops proliferation of hepatocellular carcinoma (HCC) cells and growth of liver tumors

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Coffee, Beyond Caffeine

Coffee—caffeinated or decaffeinated—protects liver and gastrointestinal cells from toxic compounds, according to Sandra Kalthoff et al. in the November issue of Gastroenterology. In many epidemiology studies, coffee consumption reduced the risk of inflammation, chronic liver diseases, hepatocellular carcinoma (HCC), and other GI disorders. Its mechanisms are unclear, however, because coffee

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