• Does Placement on a Distant Liver Waitlist Increase Chances of Transplantation?

Does Placement on a Distant Liver Waitlist Increase Chances of Transplantation?

Placement on a liver transplant waitlist outside of a patient’s home region can reduce mortality and increase odds of receiving a liver, researchers report in the October issue of Clinical Gastroenterology and Hepatology. Strategies are needed to overcome geographic differences in access to livers for transplantation, which are more likely

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  • What Happens When You Have Dysphagia After Anti-Reflux Surgery?

What Happens When You Have Dysphagia After Anti-Reflux Surgery?

In patients who develop dysphagia within a few weeks after fundoplication surgery for gastroesophageal reflux disease (GERD), most symptoms resolve with time and require no intervention. However, patients with clinically significant dysphagia months after this surgery benefit from endoscopic dilation, researchers report in the September issue of Clinical Gastroenterology and

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Is an Endoscopic Transluminal Approach Better Than Surgery for Patients With Necrotizing Pancreatitis?

An endoscopic transluminal approach for treatment of infected necrotizing pancreatitis, compared with minimally invasive surgery, significantly reduced major complications, lowered costs, and increased quality of life, according to a randomized trial published in the March issue of Gastroenterology. Acute pancreatitis is the third most common gastrointestinal disorder in the United

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  • Has MELD-Na Improved Outcomes of Patients on the Liver Transplant Waitlist?

Has MELD-Na Improved Outcomes of Patients on the Liver Transplant Waitlist?

Liver allocation based on model for end-stage liver disease-sodium (MELD-Na) score improved waitlist outcomes and provided significant benefit to patients with hyponatremia, researchers report in the November issue of Gastroenterology. However, there are discrepancies in transplantation survival benefit, so current rules for liver allocation might require revision, the authors state. The

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  • What Are the Best Endpoints for Trials of Agents for Ulcerative Colitis?

What Are the Best Endpoints for Trials of Agents for Ulcerative Colitis?

Despite advances in methods of clinical trials for ulcerative colitis (UC), there is still a large amount of variation in endpoints, even in definitions of response and remission, reseachers found in a systematic review published in the May issue of Clinical Gastroenterology and Hepatology. The authors conclude that we need a

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  • Is Endoscopic Balloon Dilation Better Than Surgery for Patients With Crohn’s Disease-related Strictures?

Is Endoscopic Balloon Dilation Better Than Surgery for Patients With Crohn’s Disease-related Strictures?

In patients with Crohn’s disease (CD), surgical treatment of ileocolonic anastomosis strictures reduces risk of further surgery compared with endoscopic balloon dilation (EBD), researchers report in the August issue of Clinical Gastroenterology and Hepatology. However, endoscopic balloon dilation (EBD) delays time until need for a second surgery; EBD should be therefore attempted first

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  • What Factors Associate With Symptom Recurrence After Anti-reflux Surgery for GERD?

What Factors Associate With Symptom Recurrence After Anti-reflux Surgery for GERD?

The most reliable factors associated with symptom recurrence after anti-reflux surgery for patients with gastroesophageal reflux disease (GERD) are a primary complaint of extraesophageal reflux symptoms and lack preoperative response to acid-suppression therapy, researchers report in the May issue of Clinical Gastroenterology and Hepatology. Approximately 10% of the US population has

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  • Which Patients Are at Greatest Risk From Mushroom Poisoning?

Which Patients Are at Greatest Risk From Mushroom Poisoning?

Almost 20% of patients with liver damage from mushroom (Amanita) poisoning and peak levels of total bilirubin greater than 2 mg/dL require liver transplantation or die, researchers report in the May issue of Clinical Gastroenterology and Hepatology. The authors show that peak level of aspartate aminotransferase (AST) below 4000 IU/L identifies

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  • Can a Smartphone App Monitor IBD Activity?

Can a Smartphone App Monitor IBD Activity?

Researchers have developed a mobile health index for remote monitoring of patients with inflammatory bowel diseases (IBD) that could be incorporated into a smartphone app. These findings are reported in the December issue of Clinical Gastroenterology and Hepatology. The shift from symptom-oriented to prevention-oriented care delivery has accelerated the development of

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  • What is the Best Way to Predict Disease Progression in Patients With Inactive HBV?

What is the Best Way to Predict Disease Progression in Patients With Inactive HBV?

In patients with chronic hepatitis B virus (HBV) infection who are negative for HBe antigen (HBeAg), monitoring levels of HB surface antigen (HBsAg) can predict disease progression, researchers report in the October issue of Clinical Gastroenterology and Hepatology. Most persons chronically infected with HBV clear HBeAg and enter an inactive carrier phase, characterized by low or undetectable

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