• What is the Best Way to Predict Disease Progression in Patients With Inactive HBV?

What is the Best Way to Predict Disease Progression in Patients With Inactive HBV?

In patients with chronic hepatitis B virus (HBV) infection who are negative for HBe antigen (HBeAg), monitoring levels of HB surface antigen (HBsAg) can predict disease progression, researchers report in the October issue of Clinical Gastroenterology and Hepatology. Most persons chronically infected with HBV clear HBeAg and enter an inactive carrier phase, characterized by low or undetectable

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  • Should Patients Undergo Endoscopic Sphincterotomy Before Receiving Self-expandable Metallic Stents?

Should Patients Undergo Endoscopic Sphincterotomy Before Receiving Self-expandable Metallic Stents?

Endoscopic sphincterotomy (ES) provides no benefit to patients receiving self-expandable metallic stents (SEMS) for a biliary stricture caused by pancreatic cancer, researchers report in the June issue of Clinical Gastroenterology and Hepatology. The randomized controlled trial showed that ES procedure did not affect number of adverse events, SEMS patency, or

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  • Can Gluten-free Diets Benefit People with Asymptomatic Celiac Disease?

Can Gluten-free Diets Benefit People with Asymptomatic Celiac Disease?

A gluten-free diet (GFD) can benefit asymptomatic patients who test positive for celiac disease based on detection of with endomysial antibodies (EMA), researchers report in the September issue of Gastroenterology. This finding supports screening of patients at risk for celiac disease. Celiac disease is a lifelong disorder caused by ingested

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Does Menopause Affect Outcomes from Roux-en-Y Gastric Bypass Surgery?

Estradiol increases body weight loss and satiation effects of Roux-en-Y gastric bypass (RYGB) in ovariectomized rats, according to the August issue of Gastroenterology. Approximately ~85% of bariatric surgery procedures are performed on women, but little is known about the effects of menopause or reproductive hormones, such as estrogen, on outcomes.

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High Rate of Complications from Colectomy for Ulcerative Colitis

Twenty-seven percent of patients who are treated for ulcerative colitis by colectomy experience postoperative complications, according to a study in the November issue of Clinical Gastroenterology and Hepatology. Most patients with ulcerative colitis are successfully treated with medication, yet some have severe colitis attacks that can be life threatening. Approximately

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How Does Deferasirox Reduce Liver Fibrosis?

Liver fibrosis is reduced in patients with iron overload β-thalassemia and hepatitis C given the iron chelator deferasirox, according to Yves Deugnier et al. in the October issue of Gastroenterology. The liver is the main site of iron accumulation in patients with iron-overload disorders. Storage of excess iron in the

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Certolizumab and Remission in Some Patients With Crohn’s Disease

The drug certolizumab pegol induces remission in patients with Crohn’s disease who have high baseline levels of inflammation, according to William Sandborn et al. in the August issue of Clinical Gastroenterology and Hepatology. Patients with moderate to severe Crohn’s disease that do not respond conventional therapy are often treated with

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Fluid Resuscitation for Acute Pancreatitis—When and With What?

Patients that are given fluid resuscitation within 24 hours of developing acute pancreatitis are less likely to experience systemic inflammatory response (SIR) or organ failure, according to a study by Matthew G. Warndorf et al. in the August issue of Clinical Gastroenterology and Hepatology. Acute pancreatitis is an inflammatory process

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