• How Does Cigarette Smoke Promote Pancreatic Tumor Development?

How Does Cigarette Smoke Promote Pancreatic Tumor Development?

Exposure to cigarette smoke activates stem cell features in pancreatic cells, via nicotinic cholinergic receptor signaling to transcription factors that activate expression of stem cell genes, researchers report in the September issue of Gastroenterology. Levels of the stem cell transcriptional regulator PAF1 are increased in pancreatic tumors from humans and

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  • VIDEO: Non-invasive Detection of Early- and Late-Stage PDAC

VIDEO: Non-invasive Detection of Early- and Late-Stage PDAC

Specific patterns of volatile organic compounds (VOCs) in urine samples can identify patients with pancreatic ductal adenocarcinoma (PDAC), researchers report in the February issue of Gastroenterology. The noninvasive technology, based on ion mobility spectrometry, can be used to discriminate between healthy individuals vs individuals with early- or advanced-stage cancer. VOCs are metabolic products of microbes that can

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