Patients receiving laparoscopic anti-reflux surgery (LARS) for chronic gastroesophageal reflux disease (GERD) had significantly greater long-term reductions in 24-hour esophageal acid exposure than patients given esomeprazole, researchers report in the May issue of Clinical Gastroenterology and Hepatology. However, both treatments controlled symptoms in most patients, and esophageal and gastric pH were notRead more
Undifferentiated or crypt-like, and differentiated or villus-like, human intestinal enteroids represent distinct points along the crypt–villus axis and can be used to characterize electrolyte transport processes along the small intestine, researchers report in the March issue of Gastroenterology. Studies of their duodenal enteroid model showed that electrogenic Na+/HCO3– cotransporter 1 in theRead more
Do Proton Pump Inhibitors Reduce the Need for Phlebotomy in Patients With Hereditary Hemochromatosis?
In certain patients with hereditary hemochromatosis (HH), treatment with proton pump inhibitors (PPIs) for 2 or more years significantly reduced the number of phlebotomies required to maintain serum levels below 100 μg/L, researchers report in the January issue of Clinical Gastroenterology and Hepatology. HH is one of the most commonRead more