• What are the Effects of Prednisolone in Patients With Severe Alcoholic Liver Disease?

What are the Effects of Prednisolone in Patients With Severe Alcoholic Liver Disease?

Infections are frequent in patients with severe alcoholic liver disease, but are only independently associated with mortality when patients receive prednisolone, researchers report in the April issue of Gastroenterology. This could offset prednisolone’s therapeutic benefit. This study’s senior author, Mark Thursz, discusses the findings in a video abstract. As with

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  • What is the Best Treatment for Severe Alcoholic Hepatitis?

What is the Best Treatment for Severe Alcoholic Hepatitis?

Corticosteroids, alone or in combination with pentoxifylline or N-acetylcysteine (NAC), reduce short-term mortality in patients with severe alcoholic hepatitis, a meta-analysis shows in the October issue of Gastroenterology. However, there is no treatment to reduce medium-term mortality, the authors find. Severe alcoholic hepatitis is characterized by progressive inflammatory injury to hepatocytes and

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