• Review: How Does the Tumor Stroma Contribute to Pancreatic Cancer Progression, and Can We Stop It?

Review: How Does the Tumor Stroma Contribute to Pancreatic Cancer Progression, and Can We Stop It?

Recently developed approaches for reshaping the pancreatic tumor stroma might be used in treatments for pancreatic cancer, according to a review in the March issue of Gastroenterology. The authors discuss relationships among the pancreatic tumor extracellular matrix, the vasculature, the immune system, and metabolism, and how these might be manipulated to stop pancreatic tumor

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  • Are Patients With PSC and Colitis More likely to Have Subclinical Inflammation?

Are Patients With PSC and Colitis More likely to Have Subclinical Inflammation?

Patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC) in remission are significantly more likely to have inflammation of the right colon, based on endoscopic and histologic markers, than patients with UC without PSC, researchers report in the January issue of Clinical Gastroenterology and Hepatology. These findings provide insight into cause

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Advances in PSC, NAFLD, and Liver Transplantation for Patients with HCV Infection reported at International Liver Congress

A chemical cousin of an existing drug shows promise for patients with primary sclerosing cholangitis (PSC), a larger waistline increases risk for severe nonalcoholic fatty liver disease (NAFLD), and livers from hepatitis C virus (HCV)-infected donors are safe for transplant into HCV-infected recipients were all among the exciting findings reported

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  • Special Issue: Managing Patients With Liver Disease

Special Issue: Managing Patients With Liver Disease

A special issue of Clinical Gastroenterology and Hepatology is dedicated to the clinical management of hepatic disorders, including nonalcoholic fatty liver disease (NAFLD), viral hepatitis, autoimmune hepatitis, and primary sclerosing cholangitis (PSC). The issue comprises 14 review articles that aim to present clinicians with evidence-based guidance and expert opinions on management of patients with liver

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  • Does Coffee Affect Development of Cholestatic Liver Disorders?

Does Coffee Affect Development of Cholestatic Liver Disorders?

Lower levels of coffee consumption are associated with primary sclerosing cholangitis (PSC), but not primary biliary cirrhosis (PBC), researchers report in the September issue of Clinical Gastroenterology and Hepatology. Coffee is considered to be a medically beneficial beverage—consumption has been associated with reductions in metabolic syndrome, cardiovascular disease, and weight

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