Does IBD Increase Risk for Oral Cancer?

Patients with inflammatory bowel diseases (IBD) have an increased risk of oral cancers—especially tongue cancer—researchers report in the March issue of Clinical Gastroenterology and Hepatology. Women are at higher risk than men. Oral cancers develop in the mucosal surfaces of the lips, floor of mouth, tongue, buccal mucosa, lower and

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Should Patients with Crohn’s Disease Continue Receiving Immunomodulators When Starting Anti-TNF Therapy?

Continued use of immunomodulator therapy in patients with Crohn’s disease receiving anti-tumor necrosis factor (TNF) therapy is no more effective than anti-TNF monotherapy in inducing or maintaining response or remission, researchers show. The meta-analysis of randomized controlled trials is published in the December issue of Clinical Gastroenterology and Hepatology. There is debate

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  • Do Patients Really Prefer Colon Capsule Endoscopy Over Colonoscopy?

Do Patients Really Prefer Colon Capsule Endoscopy Over Colonoscopy?

Slightly more than 50% of people with an inherited risk for colorectal cancer (CRC) agree to undergo screening for this cancer, and most prefer colonoscopy to colon capsule endoscopy—even though these are equally effective screening tools—researchers report in the December issue of Clinical Gastroenterology and Hepatology. Colonoscopy should therefore remain

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Deadly Bacteria Transmitted by Duodenoscopes

Duodenoscopes and endoscopes used in retrograde cholangiopancreatography are causing infections with carbapenem-resistant enterobacteriaceae (CRE) and possibly other bacteria throughout the US. While medical societies and journals scramble to increase awareness of infection risks, medical centers are already taking precautions to avoid further infections. The US Food and Drug Administration (FDA),

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  • Do Selective Serotonin Reuptake Inhibitors Increase Risk for GI Bleeding?

Do Selective Serotonin Reuptake Inhibitors Increase Risk for GI Bleeding?

Use of selective serotonin reuptake inhibitors increases risk for upper gastrointestinal bleeding (UGIB) by 55%—and even more among patients also taking nonsteroidal anti-inflammatory or antiplatelet drugs, researchers report in the January issue of Clinical Gastroenterology and Hepatology. Risk might be reduced significantly by concomitant use of acid-suppressing drugs. Selective serotonin

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Is it Safe for Patients With Cardiovascular Disease to Discontinue Low-Dose Aspirin Therapy?

In patients with cardiovascular disease, discontinuing low-dose aspirin therapy after peptic ulcer bleeding increases risk of death and acute cardiovascular events almost 7-fold, according to the January issue of Clinical Gastroenterology and Hepatology. Many patients with cardiovascular disease receive low-dose aspirin, for its cardioprotective effects. However, aspirin can also cause

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Is it Safe to Donate Part of Your Liver?

Donating part of your liver is just as safe as donating a kidney—donors of these organs have survival rates similar to the rest of the population, according to an article in the February issue of Gastroenterology. With organ shortages, live-donor liver transplantation (LDLT) is a lifesaving alternative to transplantation from deceased

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Who Will Develop Colorectal Cancer at a Young Age?

A screen for mutations in mismatch repair (MMR) genes could be used to identify young people at risk for colorectal cancer, report Paul Limburg et al. in the June issue of Clinical Gastroenterology and Hepatology. It is a challenge to identify people who are less than 50 years old that

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Surviving Childhood Cancer Increases GI Risks

Individuals who received therapy for cancer during childhood have an increased risk of developing GI complications later in life, according to Robert Goldsby et al. in the May issue of Gastroenterology. About 80% of children who receive cancer therapy survive more than 5 years; therapies can be especially toxic to

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