• What Changes Occur in the Intestine After Gastric Bypass vs Vertical Sleeve Gastrectomy ?

What Changes Occur in the Intestine After Gastric Bypass vs Vertical Sleeve Gastrectomy ?

The intestine adapts differently to Roux-en-Y gastric bypass (RYGB) than to vertical sleeve gastrectomy (VSG), researchers show in the February issue of Gastroenterology. RYGB increases intestinal glucose disposal whereas VSG delays glucose absorption, but each reduces glycemia. Bariatric surgeries such as RYGB and VSG are the most effective ways to resolve

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Preventing Weight Gain After Gastric Bypass

A procedure called transoral outlet reduction can reverse weight gain after Roux-en-Y gastric bypass (RYGB), according to a controlled clinical trial published in the July issue of Gastroenterology. Although these results were achieved using a superficial suction-based device, greater levels of weight loss could be achieved with newer, full-thickness suturing

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What are the Complications of Weight Loss Surgery?

Bariatric surgery is effective treatment for obesity and its related disorders. Yet as increasing numbers of patients undergo this procedure, gastroenterologists encounter a growing number of complications. A Perspective article in the April issue of Clinical Gastroenterology and Hepatology discusses common complications of bariatric surgery and ways to manage them. Bariatric

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Molecular Mechanisms of Roux-en-Y Gastric Bypass

Many of the beneficial effects of Roux-en-Y gastric bypass (RYGB), including improved glucose homeostasis, require the actions of melanocortin-4 receptors (MC4Rs) on autonomic neurons, according to the March issue of Gastroenterology. Fasting glycemia often improves within days of RYGB (see below figure), which produces greater improvements in glucose homeostasis than

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Does Menopause Affect Outcomes from Roux-en-Y Gastric Bypass Surgery?

Estradiol increases body weight loss and satiation effects of Roux-en-Y gastric bypass (RYGB) in ovariectomized rats, according to the August issue of Gastroenterology. Approximately ~85% of bariatric surgery procedures are performed on women, but little is known about the effects of menopause or reproductive hormones, such as estrogen, on outcomes.

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