• Who Should Undergo Surgery for Pancreatic Cysts?

Who Should Undergo Surgery for Pancreatic Cysts?

When should a patient with a pancreatic cystic lesion undergo surgery? How can we tell if the surgery will provide relief, or prevent death from pancreatic cancer, or burden a patient with an unnecessary procedure? Two articles in the October issue of Clinical Gastroenterology and Hepatology increase our understanding of

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  • VIDEO: Endoscopic Management of Gastrointestinal Leaks and Fistulae

VIDEO: Endoscopic Management of Gastrointestinal Leaks and Fistulae

Gastrointestinal leaks and fistulae can be serious acute complications or chronic conditions caused by inflammation, malignancy, or surgery. In a Perspective article in the October issue of Clinical Gastroenterology and Hepatology, Field F. Willingham and Jonathan M. Buscaglia discuss advanced endoscopic methods for less invasive treatment of these luminal defects. They explain that the main goal of

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VIDEO: Endoscopic Suturing for Ulcer Exclusion

Researchers report the use of endoscopic surgical suturing for ulcer exclusion in the July issue of Gastroenterology, and provide a video of their procedure. It is important to prevent rebleeding of peptic ulcers. A prototype endoscopic suturing device has been developed to provide hemostasis in patients with massively bleeding gastric ulcers. Philip Wai Yan Chiu et

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Is Stretta an Effective Treatment for GERD?

An expensive radiofrequency ablation technique known as Stretta does not benefit patients with gastroesophageal reflux disease (GERD), researchers report in the June issue of Clinical Gastroenterology and Hepatology. In a meta-analysis of randomized controlled studies, Seth Lipka et al found no evidence that Stretta normalized esophageal pH values, augmented lower esophageal

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  • What are the Effects of Antiviral Therapy in Patients With IBD and CMV Infection?

What are the Effects of Antiviral Therapy in Patients With IBD and CMV Infection?

Cytomegalovirus (CMV) infection complicates inflammatory bowel disease (IBD), but anti-viral therapy reduces the need for bowel surgery, researchers report in the May issue of Clinical Gastroenterology and Hepatology. The benefits of anti-viral treatment are greatest for patients with high-grade disease, they show. CMV infection is more common in patients with

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  • Is Fecal Calprotectin a Good Marker of Crohn’s Disease Recurrence?

Is Fecal Calprotectin a Good Marker of Crohn’s Disease Recurrence?

The fecal concentration of calprotectin can be used to monitor for recurrence of Crohn’s disease, with a high enough negative predictive value that physicians can be confident they won’t miss patients with recurrent disease, researchers report in the May issue of Gastroenterology. Approximately 80% of patients with Crohn’s disease require surgery

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  • What is This Liver Tumor?

What is This Liver Tumor?

Researchers describe a rare liver tumor of vascular origin in the May issue of Clinical Gastroenterology and Hepatology. Laisa Socorro Briongos-Figuero and Tomás Zamora-Martínez describe the case of a 59-year-old man with chronic pancreatitis who was was admitted to the hospital with vomiting and jaundice, without fever or diarrhea. He had a previous history of

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Bone Tumors, Abdominal Pain, and Aspirin

Physicians report an unusual case of a man with abdominal pain that responded to aspirin therapy, in the October issue of Gastroenterology. It turns out that the pain was caused by a prostaglandin-producing benign bone tumor. Harpal S. Dhaliwal et al. describe examination of a 33-year-old man with an 18-month history

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Video: Gastric to Esophageal Mucosal Transplantation

In the April issue of Gastroenterology, researchers report transplantation of mucosa from a patient’s stomach to esophagus, to prevent stricture formation after circumferential endoscopic mucosal dissection of early-stage esophageal cancer. Endoscopic submucosal resection and dissection are used to remove areas of dysplasia and cancer from the esophagus. However, stricture formation is a major drawback

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What is the Best Treatment for Esophageal Adenocarcioma?

Patients with esophageal adenocarcinoma (EAC) who receive endoscopic therapy survive as long as patients treated by surgery, according to the November issue of Clinical Gastroenterology and Hepatology. Esophageal cancer is a highly fatal malignancy—approximate 19% of patients survive 5 years. The incidence of EAC, the most common form of esophageal

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