• What is the Best Treatment Option for Fistulizing Crohn’s Disease?

What is the Best Treatment Option for Fistulizing Crohn’s Disease?

Tumor necrosis factor (TNF) antagonists are effective for induction and maintenance of perianal fistula response and remission in patients with Crohn’s disease (CD), a systematic review and meta-analysis shows in the December issue of Clinical Gastoenterology and Hepatology. However, there are few data on the effects on internal fistulae, and further studies

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  • What is the Risk of Pancreatic Cancer in Patients with Low-Risk IPMNs?

What is the Risk of Pancreatic Cancer in Patients with Low-Risk IPMNs?

Low-risk intraductal papillary mucinous neoplasms have an almost 8% chance of progressing to pancreatic cancer within 10 years, whereas higher-risk IPMNs have almost 25% chance, reports a systematic review and meta-analysis in the October issue of Clinical Gastroenterology and Hepatology. Continued long-term surveillance is therefore important for patients with low-risk, as

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  • Do Selective Serotonin Reuptake Inhibitors Increase Risk for GI Bleeding?

Do Selective Serotonin Reuptake Inhibitors Increase Risk for GI Bleeding?

Use of selective serotonin reuptake inhibitors increases risk for upper gastrointestinal bleeding (UGIB) by 55%—and even more among patients also taking nonsteroidal anti-inflammatory or antiplatelet drugs, researchers report in the January issue of Clinical Gastroenterology and Hepatology. Risk might be reduced significantly by concomitant use of acid-suppressing drugs. Selective serotonin

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