Video Abstract: Increased Risk of Cervical Cancer in Women with IBD

Women with ulcerative colitis or Crohn’s disease are at increased risk for cervical neoplasias, researchers report in the April issue of Clinical Gastroenterology and Hepatology. Christine Rungoe et al performed a population-based cohort study of 27,408 women with inflammatory bowel diseases (IBD). In her video abstract, she says “we observed that women with ulcerative

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Are Mitochondria Involved in Ulcerative Colitis?

Changes in mitochondrial DNA that increase levels of ATP in the intestinal mucosa protect mice from colitis, according to the November issue of Gastroenterology. Strategies to increase mitochondrial ATP production by intestinal epithelial cells might therefore be developed to treat patients with ulcerative colitis (UC). Characteristics of UC include reduced levels

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Can a microRNA Control Inflammation in Patients With Ulcerative Colitis?

Loss of a non-coding RNA that regulates inflammation could contribute to development of ulcerative colitis (UC) in children, according to the October issue of Gastroenterology. UC and Crohn’s disease are chronic inflammatory bowel diseases that affect adults and children. These diseases are complex, and caused by combinations of genetic and

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Are All Patients With IBD at Increased Risk for Colorectal Cancer?

Although inflammatory bowel disease (IBD) increases risk for colorectal cancer (CRC), the risk is only substantial among patients with long-term, extensive colitis. Furthermore, CRC risk is reduced by thiopurine therapy, according to the July issue of Gastroenterology. Laurent Beaugerie et al. collected data from 19,486 patients with IBD (60% with

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