• Intestinal Microbiota Protect Children From Malnutrition

Intestinal Microbiota Protect Children From Malnutrition

Three new studies show that intestinal bacteria protect children from malnutrition and allow them to benefit from breast milk. Malnutrition, the world’s leading cause of death before age 5, is a persistent challenge that is not always remedied by improvements in nutrition. This is because the community of gut microbes regulate growth,

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  • Researchers Determine how FTO Variant Increases Obesity Risk

Researchers Determine how FTO Variant Increases Obesity Risk

Variants in the FTO gene have been associated with obesity and metabolic disease, but little is known about the function of its product. Researchers now show how this gene regulates body weight. FTO encodes a nuclear protein of the AlkB related non-heme iron and 2-oxoglutarate-dependent oxygenase superfamily. In the NIH

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Preventing Weight Gain After Gastric Bypass

A procedure called transoral outlet reduction can reverse weight gain after Roux-en-Y gastric bypass (RYGB), according to a controlled clinical trial published in the July issue of Gastroenterology. Although these results were achieved using a superficial suction-based device, greater levels of weight loss could be achieved with newer, full-thickness suturing

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Does Menopause Affect Outcomes from Roux-en-Y Gastric Bypass Surgery?

Estradiol increases body weight loss and satiation effects of Roux-en-Y gastric bypass (RYGB) in ovariectomized rats, according to the August issue of Gastroenterology. Approximately ~85% of bariatric surgery procedures are performed on women, but little is known about the effects of menopause or reproductive hormones, such as estrogen, on outcomes.

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Bariatric Surgery – More Than Expected

Bariatric surgery doesn’t only cause dramatic weight loss—the procedure itself has profound metabolic effects, according to studies published in the September issue of Gastroenterology. Two types of bariatric surgery are most effective therapies for sustained weight loss in obese patients. In Roux-en-Y gastric bypass (RYGB), a gastric pouch drains into

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