• Efficacy of Endoscopic Sleeve Gastroplasty In Reducing Body Weight and Metabolic Complications

Efficacy of Endoscopic Sleeve Gastroplasty In Reducing Body Weight and Metabolic Complications

Endoscopic sleeve gastroplasty (ESG) sustains loss of total body weight for up to 24 months, and also reduces markers of hypertension, diabetes, and hypertriglyceridemia, researchers report from a prospective study published in the April issue of Clinical Gastroenterology and Hepatology. ESG is an incisionless, minimally invasive bariatric procedure that reduces the

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  • A Minimally Invasive Endoscopic Procedure Instead of Bariatric Surgery?

A Minimally Invasive Endoscopic Procedure Instead of Bariatric Surgery?

Endoscopic sleeve gastroplasty (ESG) delays gastric emptying, induces early satiation, and significantly reduces body weight, researchers report in the January issue of Clinical Gastroenterology and Hepatology. ESG could therefore be an alternative to bariatric surgery for some patients with obesity. Although bariatric surgery is the most effective therapy for obesity,

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  • A Case of Duodenal Ulcers from Strongyloides

A Case of Duodenal Ulcers from Strongyloides

Researchers describe a nearly missed case of Strongyloides infection in the April issue of Gastroenterology, had it not been for analysis of duodenal biopsies. Douglas Grunwald et al describe the case of a 74-year-old Jamaican-born woman with a 3-month history of dyspepsia, nausea, bloating, early satiety, and weight loss of 40 lbs. In

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  • Does Weight Loss Resolve Fatty Liver Disease?

Does Weight Loss Resolve Fatty Liver Disease?

Two separate studies in the August issue of Gastroenterology show that weight loss, via diet or bariatric surgery, reduce features of non-alcoholic steatohepatitis (NASH). Eduardo Vilar-Gomez et al associated extent of weight loss, produced by lifestyle changes, with level of improvement in histologic features of NASH. The highest rates of NASH reduction

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  • What’s Wrong With Herbal Supplements?

What’s Wrong With Herbal Supplements?

Herbal supplements, used by many people for weight loss and bodybuilding purposes but also to improve well-being and reduce symptoms of chronic diseases, have recently come under investigation because of uncertainty about their contents, safety, and efficacy. On February 3, the New York Times wrote that the New York State attorney general’s office accused 4 major retailers of selling

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  • Linking Herbal Supplements with Liver Injury

Linking Herbal Supplements with Liver Injury

Despite the perceived safety of herbal and dietary supplements, they can cause serious liver injury. In the July issue of Clinical Gastroenterology and Hepatology, Simona Rossi and Victor J. Navarro discuss the scope, use, and regulation of herbal and dietary supplements, as well as the diagnosis of herbal and dietary

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  • What is the Cause of this Mechanic’s Abdominal Pain?

What is the Cause of this Mechanic’s Abdominal Pain?

A 56-year-old male auto mechanic experienced fever, chills, drenching night sweats, malaise, nausea, and abdominal pain and distention for 6 weeks, associated with 15 kg of lost weight. Twenty years ago he was diagnosed with ileocolonic Crohn’s disease, but he had been asymptomatic on mercaptopurine therapy for the past 10 years. He stopped smoking

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Preventing Hypoglycemia After Gastric Bypass

Many patients who undergo gastric bypass surgery experience hypoglycemia after meals. Researchers report in the March issue of Gastroenterology that they can correct this condition with an agent that blocks the receptor for the glucagon-like peptide 1 (GLP1). Roux-en-Y gastric bypass surgery, widely used to treat obesity, alters glucose metabolism in

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How Might Carbonation Contribute to Obesity?

Carbonation makes drinks seem less sweet than they really are, and could increase consumption of sugar and food, neuroscientists report in the September issue of Gastroenterology. It might be therefore be best for weight-loss plans to avoid carbonated beverages. Addition of carbon dioxide (CO2) to water (carbonation) makes it effervescent

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Preventing Weight Gain After Gastric Bypass

A procedure called transoral outlet reduction can reverse weight gain after Roux-en-Y gastric bypass (RYGB), according to a controlled clinical trial published in the July issue of Gastroenterology. Although these results were achieved using a superficial suction-based device, greater levels of weight loss could be achieved with newer, full-thickness suturing

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