A monoclonal antibody against IL13 reduced histologic and endoscopic features of eosinophilic esophagitis (EoE) in a placebo-controlled phase 2 trial, researchers report in the February issue of Gastroenterology. The antibody, called RPC4046, was well tolerated. EoE is a chronic, immune-mediated disease of the esophagus characterized by eosinophil-mediated mucosal inflammation and esophageal dysfunction. The prevalence of EoE … Continue reading Can an Antibody Against IL13 Be Used to Treat Eosinophilic Esophagitis?
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