Technology
  • Alterations in Fecal Fungal Microbiomes of Patients With COVID-19

Alterations in Fecal Fungal Microbiomes of Patients With COVID-19

Patients hospitalized with COVID-19 have alterations in their fecal mycobiomes, including enrichment of fungal pathogens from the genera Candida and Aspergillus, compared with controls researchers report in the October issue of Gastroenterology. Unstable gut mycobiomes and prolonged dysbiosis persisted in a subset of patients with COVID-19 for as long as 12 days after nasopharyngeal

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Nutritional Risks in Adolescents After Bariatric Surgery

Adolescents undergoing vertical sleeve gastrectomy (VSG) have fewer nutritional deficiencies than Roux-en-Y bypass (RYGB) at 5 years after the procedure, but both can produce deficiencies in iron and B12, researchers report in Clinical Gastroenterology and Hepatology. Ongoing nutrient monitoring and supplementation are recommended for all patients who receive bariatric surgery. 

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Is Antibiotic Prophylaxis Necessary During EUS-FNA of Pancreatic Cystic Lesions?

Risk of infection is low in patients undergoing endoscopic ultrasound with fine-needle aspiration (EUS-FNA) of pancreatic cysts, researchers report from a randomized controlled trial published in Gastroenterology. The incidence of infections did not differ significantly with vs without ciprofloxacin prophylaxis. The risk of pancreatic cyst infection after EUS-FNA is not

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  • How Do Diet and Antibiotic Use Affect Risk of Colorectal Tumor Recurrence?

How Do Diet and Antibiotic Use Affect Risk of Colorectal Tumor Recurrence?

Researchers have identified mechanisms by which diet and antibiotic use together promote tumorigenesis by colon cancer cells at the anastomosis after colorectal surgery, reported in the March issue of Gastroenterology. Strategies to prevent emergence of these microbe communities or their enzymatic activities might be used to reduce the risk of

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What Treatments Are Effective for Chronic Nausea and Vomiting?

Gastric electrical stimulation reduces vomiting in patients with refractory chronic vomiting and/or nausea, researchers report in a randomized trial published in the February issue of Gastroenterology. Chronic nausea and vomiting are estimated to affect 2.2% of the adult population. For many patients, dietary changes and medical treatments do not improve symptoms,

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  • How Is The Intestinal Microbiome Altered in Patients With IBD and Does it Change During Therapy?

How Is The Intestinal Microbiome Altered in Patients With IBD and Does it Change During Therapy?

Treatment of inflammatory bowel diseases (IBD) with anti-tumor necrosis factor (anti-TNF) drugs restores diversity to the intestinal microbiome, researchers report in the November issue of Gastroenterology.  The study associates metabolic interactions among luminal bacteria with outcomes of therapy. Altered interactions between the mucosal immune system and intestinal microbiota contribute to

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  • How Should We Treat Recurrent Acute Pancreatitis?

How Should We Treat Recurrent Acute Pancreatitis?

Recurrent acute pancreatitis with a clear cause can be treated with endoscopy, explain Liam Zakko and Timothy B. Gardner in a “Here and Now: Clinical Practice” article in the October issue of Clinical Gastroenterology and Hepatology. Acute pancreatitis affects 40 to 50 of every 100,000 Americans per year and is the

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  • What Happens When You Have Dysphagia After Anti-Reflux Surgery?

What Happens When You Have Dysphagia After Anti-Reflux Surgery?

In patients who develop dysphagia within a few weeks after fundoplication surgery for gastroesophageal reflux disease (GERD), most symptoms resolve with time and require no intervention. However, patients with clinically significant dysphagia months after this surgery benefit from endoscopic dilation, researchers report in the September issue of Clinical Gastroenterology and

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  • What is the Best Personality for an Endoscopist?

What is the Best Personality for an Endoscopist?

Researchers show that you want your endoscopist to be a type-A person — adenoma detect rates (ADRs) are higher among physicians who describe themselves as more compulsive or thorough, researchers report in the July issue of Clinical Gastroenterology and Hepatology. There was no association between ADR and financial incentives, malpractice concerns,

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  • Lusutrombopag Reduces Need for Platelet Transfusion in Patients With Thrombocytopenia and Chronic Liver Disease

Lusutrombopag Reduces Need for Platelet Transfusion in Patients With Thrombocytopenia and Chronic Liver Disease

Lusutrombopag, an oral small molecule agonist of the thrombopoietin receptor, achieves and maintains target platelet count in patients with chronic liver disease and thrombocytopenia undergoing invasive procedures, researchers report in a phase 3, placebo-controlled trial published in the May issue of Clinical Gastroenterology and Hepatology. The drug caused no significant

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