• A Twisted Stomach

A Twisted Stomach

Researchers report a case of gastric rotation, with inversion of the greater and lesser curvatures along the long axis of the stomach, in the May issue of Gastroenterology. Fady G. Haddad et al describe a 56-year-old woman with history of peptic ulcer disease, diverticulosis, hypertension, and hypothyroidism who presented with acute post-prandial epigastric pain.

Read more
  • Leptin Mutation Causes Early-Onset Extreme Obesity

Leptin Mutation Causes Early-Onset Extreme Obesity

A mutation in the gene encoding the appetite-controlling hormone leptin (LEP) found to cause extreme obesity in a young child, researchers report. Martin Wabitsch et al describe insatiable appetite and early-onset extreme obesity in a 2-year old caused by a homozygous transversion in LEP.  The boy had a high serum

Read more

Achalasia, Pneumatic Dilation, Risks, and Repairs

Pneumatic dilation as a treatment for achalasia is more likely to cause esophageal perforations in the elderly, but these tears can be successfully treated medically, rather than surgically, according to the February issue of Clinical Gastroenterology and Hepatology. Achalasia is a rare motor disorder of the esophagus, cause by defects

Read more

Bariatric Surgery – More Than Expected

Bariatric surgery doesn’t only cause dramatic weight loss—the procedure itself has profound metabolic effects, according to studies published in the September issue of Gastroenterology. Two types of bariatric surgery are most effective therapies for sustained weight loss in obese patients. In Roux-en-Y gastric bypass (RYGB), a gastric pouch drains into

Read more