• Can Statin Use After Diagnosis of Esophageal Cancer Prolong Survival?

Can Statin Use After Diagnosis of Esophageal Cancer Prolong Survival?

Statin use after a diagnosis of esophageal adenocarcinoma, but not esophageal squamous cell carcinoma, reduces esophageal cancer–specific and all-cause mortality, researchers report in the April issue of Gastroenterology. Esophageal cancer is the fifth most common cause of cancer-related death in men and eighth most common cause in women, worldwide. Esophageal

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  • Do Symptoms of Eosinophilic Esophagitis Indicate Disease Activity?

Do Symptoms of Eosinophilic Esophagitis Indicate Disease Activity?

Lack of symptoms of eosinophilic esophagitis (EoE) does not necessarily mean a lack of disease activity, researchers report in the March issue of Gastroenterology. They found only a moderate association between symptom scores and endoscopic or histologic features of remission. EoE is a chronic, immune- or antigen-mediated esophageal disease characterized

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  • Dangers of Ingested Button Batteries

Dangers of Ingested Button Batteries

A clinical report raises awareness of the frequency of button battery ingestion by children and the importance of immediate removal of batteries lodged in the esophagus. In the September issue of Gastroenterology, Seung Han Kim et al describe the case of a 22-month-old child taken to the emergency room by

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  • What is the Cause of this Dysphagia?

What is the Cause of this Dysphagia?

A 60-year-old woman visited the hospital with nonprogressive mild esophageal dysphagia (without oropharyngeal transfer difficulties for solids) for 10 years. Her clinical examination and screening blood tests were normal. She had no previous medical problems except for carrying the hepatitis B virus. She underwent an upper gastrointestinal endoscopy, which revealed external compression and extrinsic arterial pulsations

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Video: Gastric to Esophageal Mucosal Transplantation

In the April issue of Gastroenterology, researchers report transplantation of mucosa from a patient’s stomach to esophagus, to prevent stricture formation after circumferential endoscopic mucosal dissection of early-stage esophageal cancer. Endoscopic submucosal resection and dissection are used to remove areas of dysplasia and cancer from the esophagus. However, stricture formation is a major drawback

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Putting a Cap on Acid Reflux

Researchers show that a polysaccharide ‘raft’ can float on top of acid in the stomach to block its backflow into the esophagus. It reduces reflux symptoms in patients with gastroesophageal reflux disease (GERD), according to a clinical trial the December issue of Clinical Gastroenterology and Hepatology. GERD is a common condition

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What is the Best Treatment for Esophageal Adenocarcioma?

Patients with esophageal adenocarcinoma (EAC) who receive endoscopic therapy survive as long as patients treated by surgery, according to the November issue of Clinical Gastroenterology and Hepatology. Esophageal cancer is a highly fatal malignancy—approximate 19% of patients survive 5 years. The incidence of EAC, the most common form of esophageal

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A More Effective Treatment for Achalasia

A specialized endoscopic procedure called peroral endoscopic myotomy (POEM) is a safe and effective treatment for esophageal achalasia, according to the August issue of Gastroenterology. Achalasia is an esophageal motility disorder characterized by incomplete relaxation of the lower esophageal sphincter, increased sphincter tone, and disrupted peristalsis. It causes dysphagia, regurgitation,

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Which Patients With Barrett’s Esophagus Will Develop Esophageal Cancer?

Researchers have found markers to identify patients with Barrett’s esophagus (BE) at greatest risk of developing esophageal adenocarcinoma. These are described in the August issue of Clinical Gastroenterology and Hepatology. In patients with BE, part of the normal stratified squamous epithelium of the lower esophagus is replaced with metaplastic columnar

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Are There Stem Cells in the Esophagus and Stomach?

Researchers have identified potential stem cells in human esophagus and stomach, as well as those in metaplastic esophagus that could lead to esophageal cancer, according to the April issue of Gastroenterology. Stem cells have been reported to exist in the basal layer of the human esophagus—their progeny are believed to

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