• What can we do with Gastrointestinal Organoids?

What can we do with Gastrointestinal Organoids?

Researchers review the latest discoveries from studies of tissue-derived and pluripotent stem cell–derived intestinal, gastric, esophageal, liver, and pancreatic organoids in the May issue of Gastroenterology. Studies of organoids have provided valuable information about GI development, tissue homeostasis, and disease and might be used to develop personalized medicines. In vitro organoid cultures are

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  • Should All Patients with IBS be Screened for Celiac Disease?

Should All Patients with IBS be Screened for Celiac Disease?

Screening patients with irritable bowel syndrome (IBS) or other functional gastrointestinal disorders for celiac disease isn’t much more effective than screening the general population, researchers report in the November issue of Clinical Gastroenterology and Hepatology. Celiac disease produces symptoms similar to those of IBS, such as lower abdominal pain, diarrhea,

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  • VIDEO: Endoscopic Management of Gastrointestinal Leaks and Fistulae

VIDEO: Endoscopic Management of Gastrointestinal Leaks and Fistulae

Gastrointestinal leaks and fistulae can be serious acute complications or chronic conditions caused by inflammation, malignancy, or surgery. In a Perspective article in the October issue of Clinical Gastroenterology and Hepatology, Field F. Willingham and Jonathan M. Buscaglia discuss advanced endoscopic methods for less invasive treatment of these luminal defects. They explain that the main goal of

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Do Continuous-flow Left Ventricular Assist Devices Increase Risk of GI Bleeding and Thrombosis?

Continuous-flow left ventricular assist devices increase the risk of gastrointestinal (GI) bleeding and thromboembolic events, researchers report in the September issue of Clinical Gastroenterology and Hepatology. Left ventricular assist device (LVAD) implantation results in improved survival and quality of life in patients with advanced heart failure. Continuous-flow LVADs (CF-LVADs) are

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Is it Safe for Patients With Cardiovascular Disease to Discontinue Low-Dose Aspirin Therapy?

In patients with cardiovascular disease, discontinuing low-dose aspirin therapy after peptic ulcer bleeding increases risk of death and acute cardiovascular events almost 7-fold, according to the January issue of Clinical Gastroenterology and Hepatology. Many patients with cardiovascular disease receive low-dose aspirin, for its cardioprotective effects. However, aspirin can also cause

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Do Stents Prevent Pancreatitis After ERCP?

Pancreatic duct stents reduce the incidence of pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP), according to a study published in the October issue of Clinical Gastroenterology and Hepatology. Pancreatitis is the most common and potentially serious complication following ERCP, occurring in up to 9% of patients that receive this procedure and

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