• New Approaches to IBS and IBD, But Concerns About PPIs, Highlighted at DDW

New Approaches to IBS and IBD, But Concerns About PPIs, Highlighted at DDW

A new test to identify diarrhea-predominant irritable bowel syndrome (D-IBS) and a new class of drugs to treat ulcerative colitis were presented at Digestive Disease Week (DDW) in Washington DC, May 15–19. Researchers also warned that many residents of nursing homes are being inappropriately given proton pump inhibitors (PPIs). Mark Pimentel

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  • Do Kids with Abdominal Pain Become Adults with Abdominal Pain?

Do Kids with Abdominal Pain Become Adults with Abdominal Pain?

A large proportion of children with functional abdominal pain still have frequent abdominal pain in adolescence and young adulthood, even though fewer than 1% have a gastrointestinal (GI) disease, researchers report in the December issue of Clinical Gastroenterology and Hepatology. Chronic or recurrent abdominal pain is common in childhood, affecting

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How Does an Antibiotic Reduce Symptoms of IBS?

Rifaximin alters the intestinal microbiota to prevent inflammation and visceral hyperalgesia in stressed rats, according to the February issue of Gastroenterology. These findings could explain the ability of this antibiotic to relieve symptoms of irritable bowel syndrome (IBS) in patients. Rifaximin is a broad-spectrum antibiotic that has been approved by

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New Treatment for IBS

LX1031, a drug that inhibits serotonin production, relieves symptoms and increases stool consistency in patients with nonconstipating irritable bowel syndrome (IBS), according to a study by Philip Brown et al. in the August issue of Gastroenterology. Serotonin (also called 5-hydroxytryptamine or 5-HT) is a neurotransmitter that controls mood and cognition, as

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