Does Thiopurine Therapy for IBD Increase Risk of Acute Myeloid Leukemias and Myelodysplastic Syndromes?

Past exposure to thiopurines increases the risk of myeloid disorders 7-fold among patients with inflammatory bowel diseases (IBDs), according to a prospective study in the August issue of Clinical Gastroenterology and Hepatology. Physicians should consider this finding when placing patients on thiopurine therapy, to best calculate risks and benefits. Despite

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