Does EGD Identify Causes of Abdominal Pain in Children?

Esophagogastroduodenoscopy (EGD) is a useful tool for the diagnosis of children with abdominal pain, researchers report in the June issue of Clinical Gastroenterology and Hepatology. The procedure identified disorders for which medical therapy was effective in 67% of children. Chronic abdominal pain is the most common indication for EGD in children.

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Causes and Treatment of Very-Early Onset IBD

Many infants with inflammatory bowel disease (IBD) have genetic defects that disrupt IL-10 signaling, according to the August issue of Gastroenterology. However, these children can be successfully treated by allogeneic hematopoietic stem cell transplantation, researchers report. IBD develops mostly in adolescents and young adults, but can occur in very young

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Why are Some Immunized Children Still At Risk for HBV Infection?

Despite immunization, children born to mothers with replicating HBV (marked by hepatitis B e antigen, or HBeAg) are still at risk for infection, according to the April issue of Gastroenterology. Mother-to-infant transmission is the major cause of hepatitis B virus (HBV) infection among immunized children. There have been proposals to

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Surviving Childhood Cancer Increases GI Risks

Individuals who received therapy for cancer during childhood have an increased risk of developing GI complications later in life, according to Robert Goldsby et al. in the May issue of Gastroenterology. About 80% of children who receive cancer therapy survive more than 5 years; therapies can be especially toxic to

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