• AGA Clinical Practice Update: Pause IBD Meds For Patients With COVID-19

AGA Clinical Practice Update: Pause IBD Meds For Patients With COVID-19

Patients with inflammatory bowel diseases (IBD) with COVID-19 should delay biological therapies, restarting them once symptoms are gone, says a clinical practice update from the American Gastroenterological Association (AGA). The practice update, written by David T Rubin et al, says that patients with IBD who test positive for SARS-CoV-2 but

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  • Meta-analysis: a Comprehensive Look at Gastrointestinal Effects of COVID-19
  • Meta-analysis: a Comprehensive Look at Gastrointestinal Effects of COVID-19

Meta-analysis: a Comprehensive Look at Gastrointestinal Effects of COVID-19

An analysis of data from the Hong Kong cohort of patients with COVID-19 and a meta-analysis of findings from publications found that 17.6% of patients with COVID-19 had gastrointestinal symptoms. This Gastroenterology study also reports that virus RNA was detected in stool samples from 48.1% patients—even in stool collected after

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  • COVID-19 Detected in Gastrointestinal Tract and Feces

COVID-19 Detected in Gastrointestinal Tract and Feces

SARS-CoV-2  (COVID-19) and its receptor are present in the gastrointestinal tract, even after clearance of the virus from respiratory tract, researchers report in Gastroenterology. Infection with COVID-19 causes respiratory illnesses including severe respiratory syndrome (SARS), so it infects respiratory epithelial cells and spreads via respiratory tract. However, the viral target

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  • Developing a New Combination Treatment for HBV Infection

Developing a New Combination Treatment for HBV Infection

NVR3–778, a capsid assembly modulator, reduces serum levels of hepatitis B virus (HBV) DNA and HBV RNA in mice with humanized livers and stable HBV infection, researchers report in the February issue of Gastroenterology. The combination of NVR3–778 and interferon prevented viral replication and HBV RNA particle production to a greater extent than

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